Phosphor/sulphur ratio: An indicator of malignant uterus change

Kálmán Patai, László Dévényi, Márta Hubay, Sándor Csömör, Romána Zelkó

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The purpose of the present study was to establish a correlation between gynaecological diseases (myoma, adenocarcinoma) and phosphor/sulphur (P/S) ratios of different regions of the uterus. Routine histological specimens were reexamined with the intention to select representative regions of the uteruses for element analysis. Conventional hematoxylin-eosin-stained sections were used to identify histological alterations by light microscopy. Scanning electron microscopic (SEM) and energy-dispersive spectroscopic (EDS) investigations were carried out to analyze the morphology and the related element composition of the samples. The results of the nonparametric statistical test (Wilcoxon rank-sum test) indicate that the P/S ratios were significantly higher in adenocarcinoma (0.8891 ± 0.0757) than in myoma (0.4713 ± 0.0306). P/S ratios of different pathologic regions of uteruses seem worth examining in a larger study population. Combination of routine histological examinations with element analysis of specimens may have useful applications in patients who have undergone radiation therapy and may identify a pattern for local recurrence at certain sites.

Original languageEnglish
Pages (from-to)215-217
Number of pages3
JournalOncology Research
Issue number4
Publication statusPublished - Jan 1 2005



  • Adenocarcinoma
  • Energy dispersive X-ray spectroscopy
  • Myoma
  • Phosphor/sulpur ratio

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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