Wilkinson-type complexes containing PPh3 ligands and modified by Et3N can be successfully used as catalysts for the homogeneous hydrogenation of ketones. The reaction is first order in substrate and rhodium and the rate does not depend on the partial pressure of hydrogen. Excess of the ligand (PPh3/Rh > 3) does not inhibit the reduction. The reaction between HRh(PPh3)3 and the ketone is regarded as the rate-determining step, and this is followed by a fast reaction with H2. The activity of the catalyst is not very sensitive to the structure of the substrate.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
- Materials Chemistry