Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria

Tímea O. Kóbori, Tatsuya Uzumaki, Mihály Kis, László Kovács, Ildikó Domonkos, Shigeru Itoh, Vendula Krynická, Saravanan G. Kuppusamy, Tomas Zakar, Jason Dean, L. Szilák, Josef Komenda, Z. Gombos, Bettina Ughy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Phosphatidylglycerol is an essential phospholipid for photosynthesis and other cellular processes. We investigated the role of phosphatidylglycerol in cell division and metabolism in a phophatidylglycerol-auxotrophic strain of Synechococcus PCC7942. Here we show that phosphatidylglycerol is essential for the photosynthetic electron transfer and for the oligomerisation of the photosynthetic complexes, notably, we revealed that this lipid is important for non-linear electron transport. Furthermore, we demonstrate that phosphatidylglycerol starvation elevated the expressions of proteins of nitrogen and carbon metabolism. Moreover, we show that phosphatidylglycerol-deficient cells changed the morphology, became elongated, the FtsZ ring did not assemble correctly, and subsequently the division was hindered. However, supplementation with phosphatidylglycerol restored the ring-like structure at the mid-cell region and the normal cell size, demonstrating the phosphatidylglycerol is needed for normal septum formation. Taken together, central roles of phosphatidylglycerol were revealed; it is implicated in the photosynthetic activity, the metabolism and the fission of bacteria.

Original languageEnglish
Pages (from-to)96-104
Number of pages9
JournalJournal of Plant Physiology
Volume223
DOIs
Publication statusPublished - Apr 1 2018

Fingerprint

Phosphatidylglycerols
phosphatidylglycerols
Cyanobacteria
electron transfer
metabolism
Photosynthetic Reaction Center Complex Proteins
Synechococcus
auxotrophs
Photosynthesis
cells
Electron Transport
Starvation
Cell Size
Cell Division
starvation
cell division
phospholipids
Nitrogen
Carbon
protein synthesis

Keywords

  • Division
  • Electron transport
  • Lipid
  • Phosphatidylglycerol
  • Photosynthesis

ASJC Scopus subject areas

  • Physiology
  • Agronomy and Crop Science
  • Plant Science

Cite this

Kóbori, T. O., Uzumaki, T., Kis, M., Kovács, L., Domonkos, I., Itoh, S., ... Ughy, B. (2018). Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria. Journal of Plant Physiology, 223, 96-104. https://doi.org/10.1016/j.jplph.2018.02.008

Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria. / Kóbori, Tímea O.; Uzumaki, Tatsuya; Kis, Mihály; Kovács, László; Domonkos, Ildikó; Itoh, Shigeru; Krynická, Vendula; Kuppusamy, Saravanan G.; Zakar, Tomas; Dean, Jason; Szilák, L.; Komenda, Josef; Gombos, Z.; Ughy, Bettina.

In: Journal of Plant Physiology, Vol. 223, 01.04.2018, p. 96-104.

Research output: Contribution to journalArticle

Kóbori, TO, Uzumaki, T, Kis, M, Kovács, L, Domonkos, I, Itoh, S, Krynická, V, Kuppusamy, SG, Zakar, T, Dean, J, Szilák, L, Komenda, J, Gombos, Z & Ughy, B 2018, 'Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria', Journal of Plant Physiology, vol. 223, pp. 96-104. https://doi.org/10.1016/j.jplph.2018.02.008
Kóbori, Tímea O. ; Uzumaki, Tatsuya ; Kis, Mihály ; Kovács, László ; Domonkos, Ildikó ; Itoh, Shigeru ; Krynická, Vendula ; Kuppusamy, Saravanan G. ; Zakar, Tomas ; Dean, Jason ; Szilák, L. ; Komenda, Josef ; Gombos, Z. ; Ughy, Bettina. / Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria. In: Journal of Plant Physiology. 2018 ; Vol. 223. pp. 96-104.
@article{086eab83f8764978901dddc2da70baa3,
title = "Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria",
abstract = "Phosphatidylglycerol is an essential phospholipid for photosynthesis and other cellular processes. We investigated the role of phosphatidylglycerol in cell division and metabolism in a phophatidylglycerol-auxotrophic strain of Synechococcus PCC7942. Here we show that phosphatidylglycerol is essential for the photosynthetic electron transfer and for the oligomerisation of the photosynthetic complexes, notably, we revealed that this lipid is important for non-linear electron transport. Furthermore, we demonstrate that phosphatidylglycerol starvation elevated the expressions of proteins of nitrogen and carbon metabolism. Moreover, we show that phosphatidylglycerol-deficient cells changed the morphology, became elongated, the FtsZ ring did not assemble correctly, and subsequently the division was hindered. However, supplementation with phosphatidylglycerol restored the ring-like structure at the mid-cell region and the normal cell size, demonstrating the phosphatidylglycerol is needed for normal septum formation. Taken together, central roles of phosphatidylglycerol were revealed; it is implicated in the photosynthetic activity, the metabolism and the fission of bacteria.",
keywords = "Division, Electron transport, Lipid, Phosphatidylglycerol, Photosynthesis",
author = "K{\'o}bori, {T{\'i}mea O.} and Tatsuya Uzumaki and Mih{\'a}ly Kis and L{\'a}szl{\'o} Kov{\'a}cs and Ildik{\'o} Domonkos and Shigeru Itoh and Vendula Krynick{\'a} and Kuppusamy, {Saravanan G.} and Tomas Zakar and Jason Dean and L. Szil{\'a}k and Josef Komenda and Z. Gombos and Bettina Ughy",
year = "2018",
month = "4",
day = "1",
doi = "10.1016/j.jplph.2018.02.008",
language = "English",
volume = "223",
pages = "96--104",
journal = "Journal of Plant Physiology",
issn = "0176-1617",
publisher = "Urban und Fischer Verlag GmbH und Co. KG",

}

TY - JOUR

T1 - Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria

AU - Kóbori, Tímea O.

AU - Uzumaki, Tatsuya

AU - Kis, Mihály

AU - Kovács, László

AU - Domonkos, Ildikó

AU - Itoh, Shigeru

AU - Krynická, Vendula

AU - Kuppusamy, Saravanan G.

AU - Zakar, Tomas

AU - Dean, Jason

AU - Szilák, L.

AU - Komenda, Josef

AU - Gombos, Z.

AU - Ughy, Bettina

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Phosphatidylglycerol is an essential phospholipid for photosynthesis and other cellular processes. We investigated the role of phosphatidylglycerol in cell division and metabolism in a phophatidylglycerol-auxotrophic strain of Synechococcus PCC7942. Here we show that phosphatidylglycerol is essential for the photosynthetic electron transfer and for the oligomerisation of the photosynthetic complexes, notably, we revealed that this lipid is important for non-linear electron transport. Furthermore, we demonstrate that phosphatidylglycerol starvation elevated the expressions of proteins of nitrogen and carbon metabolism. Moreover, we show that phosphatidylglycerol-deficient cells changed the morphology, became elongated, the FtsZ ring did not assemble correctly, and subsequently the division was hindered. However, supplementation with phosphatidylglycerol restored the ring-like structure at the mid-cell region and the normal cell size, demonstrating the phosphatidylglycerol is needed for normal septum formation. Taken together, central roles of phosphatidylglycerol were revealed; it is implicated in the photosynthetic activity, the metabolism and the fission of bacteria.

AB - Phosphatidylglycerol is an essential phospholipid for photosynthesis and other cellular processes. We investigated the role of phosphatidylglycerol in cell division and metabolism in a phophatidylglycerol-auxotrophic strain of Synechococcus PCC7942. Here we show that phosphatidylglycerol is essential for the photosynthetic electron transfer and for the oligomerisation of the photosynthetic complexes, notably, we revealed that this lipid is important for non-linear electron transport. Furthermore, we demonstrate that phosphatidylglycerol starvation elevated the expressions of proteins of nitrogen and carbon metabolism. Moreover, we show that phosphatidylglycerol-deficient cells changed the morphology, became elongated, the FtsZ ring did not assemble correctly, and subsequently the division was hindered. However, supplementation with phosphatidylglycerol restored the ring-like structure at the mid-cell region and the normal cell size, demonstrating the phosphatidylglycerol is needed for normal septum formation. Taken together, central roles of phosphatidylglycerol were revealed; it is implicated in the photosynthetic activity, the metabolism and the fission of bacteria.

KW - Division

KW - Electron transport

KW - Lipid

KW - Phosphatidylglycerol

KW - Photosynthesis

UR - http://www.scopus.com/inward/record.url?scp=85044103945&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044103945&partnerID=8YFLogxK

U2 - 10.1016/j.jplph.2018.02.008

DO - 10.1016/j.jplph.2018.02.008

M3 - Article

VL - 223

SP - 96

EP - 104

JO - Journal of Plant Physiology

JF - Journal of Plant Physiology

SN - 0176-1617

ER -