Pheno- and genotypic characteristics of human non-Hodgkin lymphoma xenografts.

L. Kopper, A. Bánkfalvi, R. Mihalik, J. Timár, T. Glant

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

The three human non-Hodgkin lymphoma xenografts with different morphological appearance (lymphoblastic, centroblastic, centrocytic) had many common pheno- and genotypic features positivity of B-cell markers, 14q+ chromosomal abnormality, etc.). Furthermore, two lines (HT 58 and 130) expressed lambda light chain monoclonally. The third line (HT 117) showed bigenotypic rearrangement of light genes. A set of new anti-proteoglycan markers, especially anti-chondroitin sulfate mAbs made possible to individualize the xenografts.

Original languageEnglish
Pages (from-to)455-459
Number of pages5
JournalActa histochemica. Supplementband
Volume39
Publication statusPublished - 1990

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