Pharmacology of azidomorphine

V. M. Bulaev, V. V. Zakusov, J. Knoll, O. N. Chichenkov

Research output: Contribution to journalArticle

Abstract

Acute experiments on rabbits, cats, and rats showed that new synthetic morphine-like analgesic azidomorphine surpasses morphine in its ability to inhibit synaptic transmission in thalamic structures, the cerebral cortex, and the spinal cord during nociceptive stimulation, and also is 20-100 times stronger in its analgesic activity.

Original languageEnglish
Pages (from-to)749-751
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume85
Issue number6
DOIs
Publication statusPublished - Jun 1978

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Morphine
Analgesics
Pharmacology
Synaptic Transmission
Cerebral Cortex
Rats
Spinal Cord
Cats
Rabbits
Experiments
azidomorphine

Keywords

  • azidomorphine
  • cortex
  • morphine
  • spinal cord
  • thalamus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Pharmacology of azidomorphine. / Bulaev, V. M.; Zakusov, V. V.; Knoll, J.; Chichenkov, O. N.

In: Bulletin of Experimental Biology and Medicine, Vol. 85, No. 6, 06.1978, p. 749-751.

Research output: Contribution to journalArticle

Bulaev, VM, Zakusov, VV, Knoll, J & Chichenkov, ON 1978, 'Pharmacology of azidomorphine', Bulletin of Experimental Biology and Medicine, vol. 85, no. 6, pp. 749-751. https://doi.org/10.1007/BF00806154
Bulaev, V. M. ; Zakusov, V. V. ; Knoll, J. ; Chichenkov, O. N. / Pharmacology of azidomorphine. In: Bulletin of Experimental Biology and Medicine. 1978 ; Vol. 85, No. 6. pp. 749-751.
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