1. Bathing freshwater mussels in water containing ergotamine or methylergometrine induced rhythmic coordinated movements of the foot and shell maintained in a stereotyped form for hours. The effect was weak at 10-9mol/1, moderate to strong at 1-4 × 10-8 mol/1, and irreversible to lethal at 5-8 × 10-8 mol/1. 2. Bathing mussels in serotonin (10-20 μmol/1) induced similar movements. They closely correspond to the well-known digging cycles exhibited by pelecypod molluscs during burrowing locomotion. 3. The serotonin content of central ganglia was not changed significantly in mussels exhibiting the ergot-induced locomotory movements. Ergotamine, up to 10-5-10-6 mol/1, did not affect the spontaneous and evoked liberation of serotonin, as well as the serotonin uptake. There is thus little indication of any direct influence of ergots on serotonergic mechanisms.
|Number of pages||5|
|Journal||Comparative Biochemistry and Physiology. Part C, Comparative|
|Publication status||Published - 1989|
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