Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones

G. JancsÓ, Elisabeth Kiraly, Aurelia JancsÓ-Gábor

Research output: Contribution to journalArticle

1024 Citations (Scopus)

Abstract

PHARMACOLOGICALLY evoked selective degeneration of neurones with a specific function or functioning with known transmitter substances, has been reported only in the monoaminergic neurone systems1,2. We report here that selective degeneration of neurones with a highly specific function can be produced by chemical agents in the somatosensory system as well. Capsaicin given to newborn rats induces selective degeneration of a distinct population of primary sensory neurones involved in mediation of chemogenic pain.

Original languageEnglish
Pages (from-to)741-743
Number of pages3
JournalNature
Volume270
Issue number5639
DOIs
Publication statusPublished - Dec 1 1977

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones'. Together they form a unique fingerprint.

  • Cite this