Pharmacological modulation of the heat shock response

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Citations (Scopus)

Abstract

Life presents a continuous series of stresses. Increasing the adaptation capacity of the organism is a long-term survival factor of various organisms and has become an attractive field of intensive therapeutic research. Induction of the heat shock response promotes survival after a wide variety of environmental stresses. Preclinical studies have proven that physiological and pharmacological chaperone inducers and co-inducers are an efficient therapeutic approach in different acute and chronic diseases. In this chapter, we summarize current knowledge of the current state of chaperone modulation and give a comprehensive list of the main drug candidates.

Original languageEnglish
Title of host publicationHandbook of Experimental Pharmacology
Pages417-436
Number of pages20
Volume172
DOIs
Publication statusPublished - 2006

Publication series

NameHandbook of Experimental Pharmacology
Volume172
ISSN (Print)01712004
ISSN (Electronic)18650325

Fingerprint

Therapeutic Human Experimentation
Heat-Shock Response
Acute Disease
Chronic Disease
Modulation
Pharmacology
Pharmaceutical Preparations
Therapeutics
Hot Temperature

Keywords

  • Chaperone inducers
  • Chaperones
  • Heat shock proteins
  • Heat shock response
  • Stress proteins

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Biochemistry

Cite this

Söti, C., & Csermely, P. (2006). Pharmacological modulation of the heat shock response. In Handbook of Experimental Pharmacology (Vol. 172, pp. 417-436). (Handbook of Experimental Pharmacology; Vol. 172). https://doi.org/10.1007/3-540-29717-0-17

Pharmacological modulation of the heat shock response. / Söti, C.; Csermely, P.

Handbook of Experimental Pharmacology. Vol. 172 2006. p. 417-436 (Handbook of Experimental Pharmacology; Vol. 172).

Research output: Chapter in Book/Report/Conference proceedingChapter

Söti, C & Csermely, P 2006, Pharmacological modulation of the heat shock response. in Handbook of Experimental Pharmacology. vol. 172, Handbook of Experimental Pharmacology, vol. 172, pp. 417-436. https://doi.org/10.1007/3-540-29717-0-17
Söti C, Csermely P. Pharmacological modulation of the heat shock response. In Handbook of Experimental Pharmacology. Vol. 172. 2006. p. 417-436. (Handbook of Experimental Pharmacology). https://doi.org/10.1007/3-540-29717-0-17
Söti, C. ; Csermely, P. / Pharmacological modulation of the heat shock response. Handbook of Experimental Pharmacology. Vol. 172 2006. pp. 417-436 (Handbook of Experimental Pharmacology).
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