pH Dependent C6 and C8 13C chemical shift assignment in N-acetyl neuraminic acid

Jacquelyn Gervay, G. Batta

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Heteronuclear correlation NMR spectroscopy was employed in the unambigous carbon chemical shift assignment of N-acetyl neuraminic acid at pH 1.0 and 7.0. Our results show that at pH 1.0 the C6 resonance is slightly downfield from that of C8 and at pH 7.0 the C6 and C8 chemical shifts are transposed. These experiments firmly establish carbon chemical shift assignments in N-acetyl neuraminic acid for the first time.

Original languageEnglish
Pages (from-to)3009-3012
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number19
DOIs
Publication statusPublished - May 9 1994

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Neuraminic Acids
Chemical shift
Carbon
Biomolecular Nuclear Magnetic Resonance
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
Experiments

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

pH Dependent C6 and C8 13C chemical shift assignment in N-acetyl neuraminic acid. / Gervay, Jacquelyn; Batta, G.

In: Tetrahedron Letters, Vol. 35, No. 19, 09.05.1994, p. 3009-3012.

Research output: Contribution to journalArticle

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