pH-Dependent activation of the alternative transcriptional factor σ(B) in Bacillus subtilis

Tamás Kovács, Attila Hargitai, K. Kovács, Imre Mécs

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The expression of the sigB gene of Bacillus subtilis was analysed in response to a mild acid shock. This gene is subject to σ(B)-dependent regulation. It has been found that the expression of sigB is induced as part of the acid-tolerant response. In that respect sigB is similar to the previously described gene gsiB which is also a member of the σ(B) regulon. Through this induction, the σ(B) regulon provides protection against acid shock. Besides its protective role against acid shock, no other general function could be directly associated with the σ(B) regulon. An acidification of the cytoplasmic environment induces synthesis of general stress proteins in B. subtilis. Copyright (C) 1998 Federation of European Microbiological Societies.

Original languageEnglish
Pages (from-to)323-328
Number of pages6
JournalFEMS Microbiology Letters
Volume165
Issue number2
DOIs
Publication statusPublished - Aug 15 1998

Fingerprint

Bacillus subtilis
Regulon
Transcriptional Activation
Shock
Acids
Heat-Shock Proteins
Genes
Gene Expression

Keywords

  • σ(B)
  • ATP regulation
  • Bacillus subtilis
  • pH stress
  • Signal transduction
  • Stress protein

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Microbiology

Cite this

pH-Dependent activation of the alternative transcriptional factor σ(B) in Bacillus subtilis. / Kovács, Tamás; Hargitai, Attila; Kovács, K.; Mécs, Imre.

In: FEMS Microbiology Letters, Vol. 165, No. 2, 15.08.1998, p. 323-328.

Research output: Contribution to journalArticle

Kovács, Tamás ; Hargitai, Attila ; Kovács, K. ; Mécs, Imre. / pH-Dependent activation of the alternative transcriptional factor σ(B) in Bacillus subtilis. In: FEMS Microbiology Letters. 1998 ; Vol. 165, No. 2. pp. 323-328.
@article{ac603a1004d046fcb75428d64844f8c2,
title = "pH-Dependent activation of the alternative transcriptional factor σ(B) in Bacillus subtilis",
abstract = "The expression of the sigB gene of Bacillus subtilis was analysed in response to a mild acid shock. This gene is subject to σ(B)-dependent regulation. It has been found that the expression of sigB is induced as part of the acid-tolerant response. In that respect sigB is similar to the previously described gene gsiB which is also a member of the σ(B) regulon. Through this induction, the σ(B) regulon provides protection against acid shock. Besides its protective role against acid shock, no other general function could be directly associated with the σ(B) regulon. An acidification of the cytoplasmic environment induces synthesis of general stress proteins in B. subtilis. Copyright (C) 1998 Federation of European Microbiological Societies.",
keywords = "σ(B), ATP regulation, Bacillus subtilis, pH stress, Signal transduction, Stress protein",
author = "Tam{\'a}s Kov{\'a}cs and Attila Hargitai and K. Kov{\'a}cs and Imre M{\'e}cs",
year = "1998",
month = "8",
day = "15",
doi = "10.1016/S0378-1097(98)00295-X",
language = "English",
volume = "165",
pages = "323--328",
journal = "FEMS Microbiology Letters",
issn = "0378-1097",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - pH-Dependent activation of the alternative transcriptional factor σ(B) in Bacillus subtilis

AU - Kovács, Tamás

AU - Hargitai, Attila

AU - Kovács, K.

AU - Mécs, Imre

PY - 1998/8/15

Y1 - 1998/8/15

N2 - The expression of the sigB gene of Bacillus subtilis was analysed in response to a mild acid shock. This gene is subject to σ(B)-dependent regulation. It has been found that the expression of sigB is induced as part of the acid-tolerant response. In that respect sigB is similar to the previously described gene gsiB which is also a member of the σ(B) regulon. Through this induction, the σ(B) regulon provides protection against acid shock. Besides its protective role against acid shock, no other general function could be directly associated with the σ(B) regulon. An acidification of the cytoplasmic environment induces synthesis of general stress proteins in B. subtilis. Copyright (C) 1998 Federation of European Microbiological Societies.

AB - The expression of the sigB gene of Bacillus subtilis was analysed in response to a mild acid shock. This gene is subject to σ(B)-dependent regulation. It has been found that the expression of sigB is induced as part of the acid-tolerant response. In that respect sigB is similar to the previously described gene gsiB which is also a member of the σ(B) regulon. Through this induction, the σ(B) regulon provides protection against acid shock. Besides its protective role against acid shock, no other general function could be directly associated with the σ(B) regulon. An acidification of the cytoplasmic environment induces synthesis of general stress proteins in B. subtilis. Copyright (C) 1998 Federation of European Microbiological Societies.

KW - σ(B)

KW - ATP regulation

KW - Bacillus subtilis

KW - pH stress

KW - Signal transduction

KW - Stress protein

UR - http://www.scopus.com/inward/record.url?scp=18244413576&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18244413576&partnerID=8YFLogxK

U2 - 10.1016/S0378-1097(98)00295-X

DO - 10.1016/S0378-1097(98)00295-X

M3 - Article

C2 - 9841221

AN - SCOPUS:18244413576

VL - 165

SP - 323

EP - 328

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

SN - 0378-1097

IS - 2

ER -