A PET és a kettós, független patológiai leletezés hatékonyan támogatják a rejtett primer tumorok keresését.

Translated title of the contribution: PET scan and double-independent pathologic investigations effectively support the detection of occult primary tumors

O. Ésik, Z. Szentirmay, T. Márián, M. Kásler, Péter Agoston, Erzsébet Lengyel, Tamás Pulay, L. Trón

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Following the failure of conventional diagnostic procedures, whole-body FDG-PET investigations were carried out in 42 metastatic cancer patients to localize occult primary carcinomas. During the clinical follow-up, the presence of malignant tumor was ruled out in 3 cases, and 2 patients originally believed to have carcinoma were confirmed to be suffering from a malignant hematological disease. These false diagnoses were associated with the use of imaging methods only (2 cases) or cytology only (1 case), lack of double, independent pathological investigations (2 cases) or immunophenotyping (2 cases) and the occurrence of an unrecognized rare tumor in a hospital with a small patient turnover (1 case). The discovered 11 occult primaries (4 lung, 3 breast, 2 hypopharynx and 1 base of the tongue carcinomas and 1 non-Hodgkin lymphoma) led to a 28% diagnostic efficacy of PET (11/39 malignant pathological reports). This efficacy is doubled (60%) if PET reveals <or = 5 malignant lesions and the locations of the pathological foci are tumor-specific. We suggest PET investigations in the search for occult primaries following a controlled pathological diagnosis and the failure of conventional diagnostic procedures.

Original languageHungarian
Pages (from-to)1262-1265
Number of pages4
JournalOrvosi Hetilap
Volume143
Issue number21 Suppl 3
Publication statusPublished - May 26 2002

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Positron-Emission Tomography
Carcinoma
Neoplasms
Immunophenotyping
Hypopharynx
Hematologic Diseases
Tongue
Non-Hodgkin's Lymphoma
Cell Biology
Breast
Lung

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A PET és a kettós, független patológiai leletezés hatékonyan támogatják a rejtett primer tumorok keresését. / Ésik, O.; Szentirmay, Z.; Márián, T.; Kásler, M.; Agoston, Péter; Lengyel, Erzsébet; Pulay, Tamás; Trón, L.

In: Orvosi Hetilap, Vol. 143, No. 21 Suppl 3, 26.05.2002, p. 1262-1265.

Research output: Contribution to journalArticle

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