Pervaporation aided enzymatic production of glycerol monostearate in organic solvents

Z. Ziobrowski, K. Kiss, A. Rotkegel, N. Nemestóthy, R. Krupiczka, L. Gubicza

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In this paper the enzymatic manufacture of glycerol monostearate was studied in high polar organic solvents. Water produced during the reaction has a disadvantageous effect on the reaction rate and enzyme activity. This byproduct water was removed and the water content was kept constant using a pervaporation unit which could be integrated on-line with the reaction system. The best yield (90%) after 6 h reaction time was achieved at 40°C, at seven-fold glycerol excess using dioxane as solvent. The enzymatic esterification reaction could be described by the Random Bi-Bi mechanism. A mathematical model have been estimated and experimentally verified by a set of experiments with varying and constant water contents. The experiments both in batch and integrated system (esterification-pervaporation) could be described with good accuracy by the proposed model.

Original languageEnglish
Pages (from-to)212-217
Number of pages6
JournalDesalination
Volume241
Issue number1-3
DOIs
Publication statusPublished - May 31 2009

Fingerprint

Pervaporation
Esterification
Glycerol
Organic solvents
Water content
water content
Water
Enzyme activity
reaction rate
Reaction rates
enzyme activity
Byproducts
experiment
Experiments
Mathematical models
fold
water
organic solvent
1,4-dioxane
effect

Keywords

  • Esterification
  • Glycerol monostearate
  • Modeling
  • Organic solvent
  • Pervaporation

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Mechanical Engineering
  • Chemistry(all)
  • Materials Science(all)
  • Water Science and Technology

Cite this

Pervaporation aided enzymatic production of glycerol monostearate in organic solvents. / Ziobrowski, Z.; Kiss, K.; Rotkegel, A.; Nemestóthy, N.; Krupiczka, R.; Gubicza, L.

In: Desalination, Vol. 241, No. 1-3, 31.05.2009, p. 212-217.

Research output: Contribution to journalArticle

Ziobrowski, Z. ; Kiss, K. ; Rotkegel, A. ; Nemestóthy, N. ; Krupiczka, R. ; Gubicza, L. / Pervaporation aided enzymatic production of glycerol monostearate in organic solvents. In: Desalination. 2009 ; Vol. 241, No. 1-3. pp. 212-217.
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