Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia: Results of the HAT Observational Study in Central and Eastern European Countries

Martin Haluzik, Adam Kretowski, Krzysztof Strojek, Leszek Czupryniak, Andrej Janez, Peter Kempler, Michal Andel, Tsvetalina Tankova, Mihail Boyanov, Lea Smircic Duvnjak, L. Madácsy, Iwona Tarnowska, Marcin Zychma, Nebojsa Lalic

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: The aim of this study was to determine the level of awareness of hypoglycemia, the level of fear for hypoglycemia, and the response to hypoglycemic events among insulin-treated diabetes patients from Central and Eastern Europe (CEE). The impact of hypoglycemia on the use of healthcare resources and patient productivity was also assessed. Methods: This was a multicenter, non-interventional, two-part, patient self-reported questionnaire study that comprised both a retrospective cross-sectional evaluation and a prospective observational evaluation. Study participants were insulin-treated adult patients with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) from CEE. Results: Most patients (85.4% T1DM and 83.6% T2DM) reported normal hypoglycemia awareness. The median hypoglycemia fear score was 5 out of 10 for T1DM and 4 out of 10 for T2DM patients. Patients increased glucose monitoring, consulted a doctor/nurse, and/or reduced the insulin dose in response to hypoglycemia. As a consequence of hypoglycemia, patients took leave from work/studies or arrived late and/or left early. Hospitalization was required for 31 (1.2%) patients with T1DM and 66 (2.1%) patients with T2DM. Conclusion: Hypoglycemia impacts patients’ personal and social functioning, reduces productivity, and results in additional costs, both direct (related to increased use of healthcare resources) and indirect related to absenteeism. Funding: Novo Nordisk.

Original languageEnglish
Pages (from-to)727-741
Number of pages15
JournalDiabetes Therapy
Volume9
Issue number2
DOIs
Publication statusPublished - Apr 1 2018

Fingerprint

Hypoglycemia
Type 2 Diabetes Mellitus
Observational Studies
Insulin
Type 1 Diabetes Mellitus
Eastern Europe
Fear
Delivery of Health Care
Efficiency
Absenteeism
Hypoglycemic Agents
Hospitalization
Nurses
Costs and Cost Analysis
Glucose

Keywords

  • Diabetes
  • Healthcare costs
  • Hypoglycemia
  • Hypoglycemia fear
  • Insulin therapy

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia : Results of the HAT Observational Study in Central and Eastern European Countries. / Haluzik, Martin; Kretowski, Adam; Strojek, Krzysztof; Czupryniak, Leszek; Janez, Andrej; Kempler, Peter; Andel, Michal; Tankova, Tsvetalina; Boyanov, Mihail; Smircic Duvnjak, Lea; Madácsy, L.; Tarnowska, Iwona; Zychma, Marcin; Lalic, Nebojsa.

In: Diabetes Therapy, Vol. 9, No. 2, 01.04.2018, p. 727-741.

Research output: Contribution to journalArticle

Haluzik, M, Kretowski, A, Strojek, K, Czupryniak, L, Janez, A, Kempler, P, Andel, M, Tankova, T, Boyanov, M, Smircic Duvnjak, L, Madácsy, L, Tarnowska, I, Zychma, M & Lalic, N 2018, 'Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia: Results of the HAT Observational Study in Central and Eastern European Countries', Diabetes Therapy, vol. 9, no. 2, pp. 727-741. https://doi.org/10.1007/s13300-018-0388-2
Haluzik, Martin ; Kretowski, Adam ; Strojek, Krzysztof ; Czupryniak, Leszek ; Janez, Andrej ; Kempler, Peter ; Andel, Michal ; Tankova, Tsvetalina ; Boyanov, Mihail ; Smircic Duvnjak, Lea ; Madácsy, L. ; Tarnowska, Iwona ; Zychma, Marcin ; Lalic, Nebojsa. / Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia : Results of the HAT Observational Study in Central and Eastern European Countries. In: Diabetes Therapy. 2018 ; Vol. 9, No. 2. pp. 727-741.
@article{4eb8b47256c44fec81e19d7f21d5b3a9,
title = "Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia: Results of the HAT Observational Study in Central and Eastern European Countries",
abstract = "Introduction: The aim of this study was to determine the level of awareness of hypoglycemia, the level of fear for hypoglycemia, and the response to hypoglycemic events among insulin-treated diabetes patients from Central and Eastern Europe (CEE). The impact of hypoglycemia on the use of healthcare resources and patient productivity was also assessed. Methods: This was a multicenter, non-interventional, two-part, patient self-reported questionnaire study that comprised both a retrospective cross-sectional evaluation and a prospective observational evaluation. Study participants were insulin-treated adult patients with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) from CEE. Results: Most patients (85.4{\%} T1DM and 83.6{\%} T2DM) reported normal hypoglycemia awareness. The median hypoglycemia fear score was 5 out of 10 for T1DM and 4 out of 10 for T2DM patients. Patients increased glucose monitoring, consulted a doctor/nurse, and/or reduced the insulin dose in response to hypoglycemia. As a consequence of hypoglycemia, patients took leave from work/studies or arrived late and/or left early. Hospitalization was required for 31 (1.2{\%}) patients with T1DM and 66 (2.1{\%}) patients with T2DM. Conclusion: Hypoglycemia impacts patients’ personal and social functioning, reduces productivity, and results in additional costs, both direct (related to increased use of healthcare resources) and indirect related to absenteeism. Funding: Novo Nordisk.",
keywords = "Diabetes, Healthcare costs, Hypoglycemia, Hypoglycemia fear, Insulin therapy",
author = "Martin Haluzik and Adam Kretowski and Krzysztof Strojek and Leszek Czupryniak and Andrej Janez and Peter Kempler and Michal Andel and Tsvetalina Tankova and Mihail Boyanov and {Smircic Duvnjak}, Lea and L. Mad{\'a}csy and Iwona Tarnowska and Marcin Zychma and Nebojsa Lalic",
year = "2018",
month = "4",
day = "1",
doi = "10.1007/s13300-018-0388-2",
language = "English",
volume = "9",
pages = "727--741",
journal = "Diabetes Therapy",
issn = "1869-6953",
publisher = "Springer Publishing Company",
number = "2",

}

TY - JOUR

T1 - Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia

T2 - Results of the HAT Observational Study in Central and Eastern European Countries

AU - Haluzik, Martin

AU - Kretowski, Adam

AU - Strojek, Krzysztof

AU - Czupryniak, Leszek

AU - Janez, Andrej

AU - Kempler, Peter

AU - Andel, Michal

AU - Tankova, Tsvetalina

AU - Boyanov, Mihail

AU - Smircic Duvnjak, Lea

AU - Madácsy, L.

AU - Tarnowska, Iwona

AU - Zychma, Marcin

AU - Lalic, Nebojsa

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Introduction: The aim of this study was to determine the level of awareness of hypoglycemia, the level of fear for hypoglycemia, and the response to hypoglycemic events among insulin-treated diabetes patients from Central and Eastern Europe (CEE). The impact of hypoglycemia on the use of healthcare resources and patient productivity was also assessed. Methods: This was a multicenter, non-interventional, two-part, patient self-reported questionnaire study that comprised both a retrospective cross-sectional evaluation and a prospective observational evaluation. Study participants were insulin-treated adult patients with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) from CEE. Results: Most patients (85.4% T1DM and 83.6% T2DM) reported normal hypoglycemia awareness. The median hypoglycemia fear score was 5 out of 10 for T1DM and 4 out of 10 for T2DM patients. Patients increased glucose monitoring, consulted a doctor/nurse, and/or reduced the insulin dose in response to hypoglycemia. As a consequence of hypoglycemia, patients took leave from work/studies or arrived late and/or left early. Hospitalization was required for 31 (1.2%) patients with T1DM and 66 (2.1%) patients with T2DM. Conclusion: Hypoglycemia impacts patients’ personal and social functioning, reduces productivity, and results in additional costs, both direct (related to increased use of healthcare resources) and indirect related to absenteeism. Funding: Novo Nordisk.

AB - Introduction: The aim of this study was to determine the level of awareness of hypoglycemia, the level of fear for hypoglycemia, and the response to hypoglycemic events among insulin-treated diabetes patients from Central and Eastern Europe (CEE). The impact of hypoglycemia on the use of healthcare resources and patient productivity was also assessed. Methods: This was a multicenter, non-interventional, two-part, patient self-reported questionnaire study that comprised both a retrospective cross-sectional evaluation and a prospective observational evaluation. Study participants were insulin-treated adult patients with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) from CEE. Results: Most patients (85.4% T1DM and 83.6% T2DM) reported normal hypoglycemia awareness. The median hypoglycemia fear score was 5 out of 10 for T1DM and 4 out of 10 for T2DM patients. Patients increased glucose monitoring, consulted a doctor/nurse, and/or reduced the insulin dose in response to hypoglycemia. As a consequence of hypoglycemia, patients took leave from work/studies or arrived late and/or left early. Hospitalization was required for 31 (1.2%) patients with T1DM and 66 (2.1%) patients with T2DM. Conclusion: Hypoglycemia impacts patients’ personal and social functioning, reduces productivity, and results in additional costs, both direct (related to increased use of healthcare resources) and indirect related to absenteeism. Funding: Novo Nordisk.

KW - Diabetes

KW - Healthcare costs

KW - Hypoglycemia

KW - Hypoglycemia fear

KW - Insulin therapy

UR - http://www.scopus.com/inward/record.url?scp=85044542516&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044542516&partnerID=8YFLogxK

U2 - 10.1007/s13300-018-0388-2

DO - 10.1007/s13300-018-0388-2

M3 - Article

AN - SCOPUS:85044542516

VL - 9

SP - 727

EP - 741

JO - Diabetes Therapy

JF - Diabetes Therapy

SN - 1869-6953

IS - 2

ER -