Personality traits, depression, and objectively measured adherence to once-daily prostaglandin analog medication in glaucoma

Gábor Holló, Péter Kóthy, Anna Géczy, Péter Vargha

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

PURPOSE: To investigate the influence of personality traits, depression, and training on objectively measured adherence to once-daily prostaglandin analog medication. METHODS: Adherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-administered travoprost. Before the 3-month data-collection period all patients received training on use of the device. Psychologic characteristics were measured using the State-Trait Anxiety Inventory, Eysenck Personality Questionnaire, and Beck Hopeless Scale and Depression Inventory. An adherent day was defined as travoprost instillation at 9 PM ±2 hours. RESULTS: Adherence was 77% for the total period. Social desirability was higher than normal (U test, P<0.0001). Seven patients (12.1%) showed mild-to-moderate depression, which was not significantly associated with decreased adherence (Kruskal-Wallis test, P=0.071). Severity of glaucoma, number of ocular and systemic medications, satisfaction with the recording device, and socio-economic characteristics had no influence on adherence. CONCLUSIONS: Objectively measured adherence to once-daily prostaglandin analog medication was good, and not influenced by treatment characteristics or patient factors including mild-to-moderate depression. The elevated social desirability suggests that self-reported adherence is not a reliable measure of adherence in glaucoma.

Original languageEnglish
Pages (from-to)288-292
Number of pages5
JournalJournal of glaucoma
Volume18
Issue number4
DOIs
Publication statusPublished - Apr 1 2009

Keywords

  • Adherence
  • Compliance
  • Depression
  • Glaucoma
  • Personality traits
  • Travalert dosing aid

ASJC Scopus subject areas

  • Ophthalmology

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