Periodically interrupted amperometry. A way of improving analytical performance of membrane coated electrodes

Livia Nagy, Nikoletta Kálmán, Géza Nagy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Amperometry is a powerful voltammetric measuring method. Its application is specially advantageous when used in combination with a separation step or with some other sample treatment method providing selectivity. The selectivity is often achieved by coating the amperometric working electrode surface with a membrane of special character. Size exclusion membrane, immobilized enzyme containing reaction layer, protecting dialysis membrane, perm selective ion exchange film etc can be mentioned here. In conventional amperometry the measuring potential is continuously applied, therefore in case of membrane coated electrodes the electrode process depletes the diffusion layer. In this work the performance of a new periodically interrupted amperometric (PIA) measuring program has been investigated in case of glucose enzyme sensor. The measuring program allowing time for reloading the diffusion layer provided higher current and therefore improved sensitivity and lower limit of detection.

Original languageEnglish
Pages (from-to)133-141
Number of pages9
JournalJournal of biochemical and biophysical methods
Volume69
Issue number1-2
DOIs
Publication statusPublished - Nov 30 2006

Keywords

  • Glucose enzyme sensor
  • Pulsed amperometry
  • Sensitivity

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry

Fingerprint Dive into the research topics of 'Periodically interrupted amperometry. A way of improving analytical performance of membrane coated electrodes'. Together they form a unique fingerprint.

  • Cite this