A perinatalis hormonalis imprinting es jelentosege

Translated title of the contribution: Perinatal hormonal imprinting and its importance

Research output: Contribution to journalArticle

Abstract

Hormonal (chemical) imprinting - developing at an evolutionary strength and having a basic role in the ontogeny of the recognition system - takes place perinatally, at the first encounter between the maturing receptor and the appropriate hormone. In the presence of the hormone there is a completion of receptor maturation and it reaches its binding capacity characteristic to the adulthood. The imprinting is executed in a given - predetermined - time interval and its effect is lifelong. As the discriminating capacity of the developing receptor is not perfect, during the receptor induction window is open, molecules belonging to the same hormone family, synthetic hormone analogues, and foreign ligands capable to bind to the same receptor family or hormone-like environmental (polluting) molecules can cause faulty imprinting. This results in the misdevelopment of the receptor, causing faulty receptor function and aberrant answer of the receptor-bearing cell. The faulty imprinting can occur - sometimes in quantities - as medicinal (iatrogenic) injury or as a consequence of environmental pollution, causing disturbances in the function of the endocrine system, in the morphology and function of cells (organs) influenced and in sexual behavior.

Original languageHungarian
Pages (from-to)620-626
Number of pages7
JournalLege Artis Medicinae
Volume9
Issue number9
Publication statusPublished - 1999

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Hormones
Environmental Pollution
Endocrine System
Sexual Behavior
Imprinting (Psychology)
Ligands
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A perinatalis hormonalis imprinting es jelentosege. / Csaba, G.

In: Lege Artis Medicinae, Vol. 9, No. 9, 1999, p. 620-626.

Research output: Contribution to journalArticle

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