Periictal heart rate variability analysis suggests long-term postictal autonomic disturbance in epilepsy

V. Toth, L. Hejjel, A. Fogarasi, C. Gyimesi, G. Orsi, A. Szűcs, N. Kovács, S. Komoly, A. Ebner, J. Janszky

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Background: One of the possible pathomechanisms of sudden death in epilepsy (SUDEP) is a postictal dysregulation of autonomic nervous system. We performed a heart rate variability (HRV) analysis of the periictal state to analyze whether a cardiac autonomic disturbance exists after an epileptic seizure. Methods: We included 31 periictal video-EEG-ECG recordings of 31 patients with epilepsy who had consecutively undergone pre-surgical evaluation. Nine generalized tonic-clonic (GTCS), 15 complex partial, and seven simple motor seizures were included. HRV was evaluated by analyzing 5-min-long ECG epochs, sampling from baseline, direct preictal, early-postictal (

Original languageEnglish
Pages (from-to)780-787
Number of pages8
JournalEuropean Journal of Neurology
Volume17
Issue number6
DOIs
Publication statusPublished - 2010

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Epilepsy
Heart Rate
Electrocardiography
Autonomic Nervous System
Sudden Death
Electroencephalography
Seizures

Keywords

  • ECG
  • Generalized tonic-clonic seizures
  • Seizure
  • Sudden unexpected death

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Periictal heart rate variability analysis suggests long-term postictal autonomic disturbance in epilepsy. / Toth, V.; Hejjel, L.; Fogarasi, A.; Gyimesi, C.; Orsi, G.; Szűcs, A.; Kovács, N.; Komoly, S.; Ebner, A.; Janszky, J.

In: European Journal of Neurology, Vol. 17, No. 6, 2010, p. 780-787.

Research output: Contribution to journalArticle

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AU - Orsi, G.

AU - Szűcs, A.

AU - Kovács, N.

AU - Komoly, S.

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