Peptide and protein folding

G. A. Chasse, A. M. Rodriguez, M. L. Mak, E. Deretey, A. Perczel, C. P. Sosa, R. D. Enriz, I. G. Csizmadia

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Ab initio peptide folding, and its role in the reductionistic approach towards the understanding of protein folding are discussed from the points of view of past, present and possible future developments. It is believed that after the initial holistic approach, we are now at a new epoch, which will be dominated by reductionism. New quantitative mathematical models will be the result of the reductionistic approach that will lead toward a new, more sophisticated holistic era.

Original languageEnglish
Pages (from-to)319-361
Number of pages43
JournalJournal of Molecular Structure: THEOCHEM
Volume537
Issue number1
DOIs
Publication statusPublished - Mar 12 2001

Keywords

  • Peptide folding
  • Protein folding
  • Reductionism and Holism

ASJC Scopus subject areas

  • Biochemistry
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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  • Cite this

    Chasse, G. A., Rodriguez, A. M., Mak, M. L., Deretey, E., Perczel, A., Sosa, C. P., Enriz, R. D., & Csizmadia, I. G. (2001). Peptide and protein folding. Journal of Molecular Structure: THEOCHEM, 537(1), 319-361. https://doi.org/10.1016/S0166-1280(00)00687-4