Extraoesophagealis reflux betegség a tünetek patofiziológiai háttere, a diagnózis és kezelés lehetoségei

Translated title of the contribution: Pathophysiology, diagnosis and therapy of the extra-oesophageal manifestations of gastro-oesophageal reflux disease

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Recently, considerable interest has been focused on the extra-oesophageal manifestations of gastro-oesophageal reflux disease. Vago-vagal reflex mechanisms have been shown to play a leading role in the pathogenesis of the extra-oesophageal manifestations. In addition, proximal reflux and subsequent chemical irritation of the respiratory tract mucosa are important factors in the development of respiratory symptoms. In contrast to the uncomplicated cases of gastro-oesophageal reflux disease, the recognition of these variations may pose a diagnostic challenge right because of the lack of typical symptoms. Successful diagnosis rests with the cooperation of the general practitioner, the specialist observing the extra-oesophageal symptom and the gastroenterologist. The establishment of the pathogenic role of gastro-oesophageal reflux may require verification by oesophageal functional tests. Treatment is based on long-term administration (for at least 3 months if respiratory symptoms are present) of an increased-dose proton pump inhibitor. In the long term, laparoscopic anti-reflux surgery is a realistic alternative to medical treatment in suitable patients. Dietary and life-style education of patients has an important complementary role in the successful long term management.

Original languageHungarian
Pages (from-to)205-211
Number of pages7
JournalLege Artis Medicinae
Volume17
Issue number3
Publication statusPublished - Mar 2007

Fingerprint

Esophageal Diseases
Gastroesophageal Reflux
Respiratory Mucosa
Proton Pump Inhibitors
Patient Education
Respiratory System
General Practitioners
Reflex
Life Style
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Extraoesophagealis reflux betegség a tünetek patofiziológiai háttere, a diagnózis és kezelés lehetoségei. / Rosztóczy, A.

In: Lege Artis Medicinae, Vol. 17, No. 3, 03.2007, p. 205-211.

Research output: Contribution to journalArticle

@article{7101de91b4dd40478b9e5e3341ae5044,
title = "Extraoesophagealis reflux betegs{\'e}g a t{\"u}netek patofiziol{\'o}giai h{\'a}ttere, a diagn{\'o}zis {\'e}s kezel{\'e}s lehetos{\'e}gei",
abstract = "Recently, considerable interest has been focused on the extra-oesophageal manifestations of gastro-oesophageal reflux disease. Vago-vagal reflex mechanisms have been shown to play a leading role in the pathogenesis of the extra-oesophageal manifestations. In addition, proximal reflux and subsequent chemical irritation of the respiratory tract mucosa are important factors in the development of respiratory symptoms. In contrast to the uncomplicated cases of gastro-oesophageal reflux disease, the recognition of these variations may pose a diagnostic challenge right because of the lack of typical symptoms. Successful diagnosis rests with the cooperation of the general practitioner, the specialist observing the extra-oesophageal symptom and the gastroenterologist. The establishment of the pathogenic role of gastro-oesophageal reflux may require verification by oesophageal functional tests. Treatment is based on long-term administration (for at least 3 months if respiratory symptoms are present) of an increased-dose proton pump inhibitor. In the long term, laparoscopic anti-reflux surgery is a realistic alternative to medical treatment in suitable patients. Dietary and life-style education of patients has an important complementary role in the successful long term management.",
keywords = "Anti reflux surgery, Extra-oesophageal reflux disease, Gastro-oesophageal reflux, Proton pump inhibitors",
author = "A. Roszt{\'o}czy",
year = "2007",
month = "3",
language = "Hungarian",
volume = "17",
pages = "205--211",
journal = "Lege Artis Medicinae",
issn = "0866-4811",
publisher = "Literatura Medica Publishing House",
number = "3",

}

TY - JOUR

T1 - Extraoesophagealis reflux betegség a tünetek patofiziológiai háttere, a diagnózis és kezelés lehetoségei

AU - Rosztóczy, A.

PY - 2007/3

Y1 - 2007/3

N2 - Recently, considerable interest has been focused on the extra-oesophageal manifestations of gastro-oesophageal reflux disease. Vago-vagal reflex mechanisms have been shown to play a leading role in the pathogenesis of the extra-oesophageal manifestations. In addition, proximal reflux and subsequent chemical irritation of the respiratory tract mucosa are important factors in the development of respiratory symptoms. In contrast to the uncomplicated cases of gastro-oesophageal reflux disease, the recognition of these variations may pose a diagnostic challenge right because of the lack of typical symptoms. Successful diagnosis rests with the cooperation of the general practitioner, the specialist observing the extra-oesophageal symptom and the gastroenterologist. The establishment of the pathogenic role of gastro-oesophageal reflux may require verification by oesophageal functional tests. Treatment is based on long-term administration (for at least 3 months if respiratory symptoms are present) of an increased-dose proton pump inhibitor. In the long term, laparoscopic anti-reflux surgery is a realistic alternative to medical treatment in suitable patients. Dietary and life-style education of patients has an important complementary role in the successful long term management.

AB - Recently, considerable interest has been focused on the extra-oesophageal manifestations of gastro-oesophageal reflux disease. Vago-vagal reflex mechanisms have been shown to play a leading role in the pathogenesis of the extra-oesophageal manifestations. In addition, proximal reflux and subsequent chemical irritation of the respiratory tract mucosa are important factors in the development of respiratory symptoms. In contrast to the uncomplicated cases of gastro-oesophageal reflux disease, the recognition of these variations may pose a diagnostic challenge right because of the lack of typical symptoms. Successful diagnosis rests with the cooperation of the general practitioner, the specialist observing the extra-oesophageal symptom and the gastroenterologist. The establishment of the pathogenic role of gastro-oesophageal reflux may require verification by oesophageal functional tests. Treatment is based on long-term administration (for at least 3 months if respiratory symptoms are present) of an increased-dose proton pump inhibitor. In the long term, laparoscopic anti-reflux surgery is a realistic alternative to medical treatment in suitable patients. Dietary and life-style education of patients has an important complementary role in the successful long term management.

KW - Anti reflux surgery

KW - Extra-oesophageal reflux disease

KW - Gastro-oesophageal reflux

KW - Proton pump inhibitors

UR - http://www.scopus.com/inward/record.url?scp=34247144156&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247144156&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:34247144156

VL - 17

SP - 205

EP - 211

JO - Lege Artis Medicinae

JF - Lege Artis Medicinae

SN - 0866-4811

IS - 3

ER -