Pathology of goose haemorrhagic polyomavirus infection in goose embryos

Sándor Bernáth, Attila Farsang, Andrea Kovács, Edith Nagy, M. Dobos-Kovács

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Goose embryos were infected with goose haemorrhagic polyomavirus (GHPV) onto the chorioallantoic membrane (CAM) in order to examine the effect of GHPV on the embryos and to obtain data on whether embryos could develop into infected, virus-shedding goslings, as well as to present an accurate biological method for virus titration. The reported method of infection could offer a possibility to express the virus titre as the median embryo infective dose (EID50). As a special pathological feature of the disease, extensive cerebral haemorrhages were observed, which protruded the skullcap in many cases. Some embryos infected with 101.25 or 100.25 EID 50/0.2 ml were able to hatch; however, they were in poor physical condition and died by post-hatching day 4 showing haemorrhagic nephritis and enteritis of geese. Virus shedding was revealed by polymerase chain reaction. The ability of some of the infected goose embryos to hatch may indicate the potency of GHPV to spread vertically, although this needs further study for confirmation.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalAvian Pathology
Volume35
Issue number1
DOIs
Publication statusPublished - Feb 2006

Fingerprint

Polyomavirus Infections
Polyomavirus
Geese
geese
embryo (animal)
Embryonic Structures
Pathology
infection
Virus Shedding
viral shedding
Scutellaria
goslings
Chorioallantoic Membrane
chorioallantoic membrane
nephritis
Enteritis
Nephritis
Cerebral Hemorrhage
enteritis
viral load

ASJC Scopus subject areas

  • Immunology
  • veterinary(all)

Cite this

Pathology of goose haemorrhagic polyomavirus infection in goose embryos. / Bernáth, Sándor; Farsang, Attila; Kovács, Andrea; Nagy, Edith; Dobos-Kovács, M.

In: Avian Pathology, Vol. 35, No. 1, 02.2006, p. 49-52.

Research output: Contribution to journalArticle

Bernáth, Sándor ; Farsang, Attila ; Kovács, Andrea ; Nagy, Edith ; Dobos-Kovács, M. / Pathology of goose haemorrhagic polyomavirus infection in goose embryos. In: Avian Pathology. 2006 ; Vol. 35, No. 1. pp. 49-52.
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