Pathological characteristics of surgically removed craniopharyngiomas: Analysis of 131 cases

G. T. Szeifert, L. Sipos, M. Horváth, M. H. Sarker, O. Major, B. Salomváry, S. Czirják, K. Bálint, F. Slowik, L. Kolonics, E. Pásztor

Research output: Contribution to journalArticle

35 Citations (Scopus)


Pathological specimens of 131 surgically removed craniopharyngiomas were obtained from the registry of the National Institute of Neurosurgery. Budapest between 1977 and 1991. The cases were reviewed statistically with reference to their gross and microscopic features and clinical characteristics, Macroscopically, 34% of the tumours were cystic, 23% solid and 43% mixed. Histologically, 38% of the cases belonged to the adamantinous group, 26% were squamous epithelial type, 15% were combined, that is expressing the characteristics of both. In 21% of the cases the surgically removed samples did not contain enough material for correct histopathological classification. There was no recurrence in the group with the squamous epithelial type tumours, while 59% of the adamantinous, and 36% of the combined Craniopharyngiomas recurred. The 5-year survival proportion was 73% at the squamous epithelial, 60% in the adamantinous. and 55% at the combined histological types.

Original languageEnglish
Pages (from-to)139-143
Number of pages5
JournalActa neurochirurgica
Issue number2-4
Publication statusPublished - Jun 1 1993



  • Craniopharyngioma
  • histopathology
  • recurrence
  • survival

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Szeifert, G. T., Sipos, L., Horváth, M., Sarker, M. H., Major, O., Salomváry, B., Czirják, S., Bálint, K., Slowik, F., Kolonics, L., & Pásztor, E. (1993). Pathological characteristics of surgically removed craniopharyngiomas: Analysis of 131 cases. Acta neurochirurgica, 124(2-4), 139-143.