Pathological alterations in human tendons

L. Józsa, A. Réffy, P. Kannus, S. Demel, E. Elek

Research output: Contribution to journalArticle

78 Citations (Scopus)


The present authors analyzed the pathological alterations of 1966 tendons examined in the National Institute of Traumatology, Budapest, during the past 18 years. The majority of cases proved to be tendinopathies ( (hypoxic-degenerative tendinopathy or calcific tendinitis, tendolipomatosis and mucoid degeneration) leading to tendon rupture. The incidence of tendon tumors, foreign bodies, infectious tendon diseases, and other pathological conditions was clearly lower. The methods of tissue preparation and of examination of tendon specimens were also evaluated. Light microscopy was sufficient for the diagnosis of pyogenic tendinitis, tumors, xanthoma, gout, and gangrene. In degenerative tendinopathies and alterations due to hereditary disease, electron microscopy was necessary. Polarization microscopy had a key role in examination of collagen structure and architecture, and identification of foreign bodies in the tendons. Enzyme histochemical and immunohistochemical examination were reliable but not absolutely necessary in the diagnosis of tendon pathology.

Original languageEnglish
Pages (from-to)15-21
Number of pages7
JournalArchives of Orthopaedic and Trauma Surgery
Issue number1
Publication statusPublished - Dec 1 1990

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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