Chronic urticaria (CU) is defined as daily wheals for at least 6 weeks or longer. Physical urticaria must be excluded. Chronic urticaria is common, occurring in 0.1% of the population. Pseudoallergic reactions to foods and infections can be causative. Based on autologous skin test reactivity and wheal-producing IgG-type autoantibodies against the high affinity IgE receptor (Fc- RI ), chronic urticaria is considered as an autoimmune disease in about one third to one half of patients. Recent reports raised the possibility that Helicobacter pylori (Hp) might play a role in CU. The authors give a summary of the pathomechanism, with their results. According to their findings, 30% of their CU patients were classified as autoimmune CUs. A trigger role of Hp in the pathogenesis of CU was proven.
|Translated title of the contribution||Pathogenetic mechanisms of chronic urticaria|
|Number of pages||6|
|Publication status||Published - Dec 1 2006|
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