A Wilson-kór patomechanizmusa és gyógyszeres kezelése

Translated title of the contribution: Pathogenesis and treatment of Wilson's disease

Judit Nagy, Zoltán Vincze, Anikó Folhoffer, Andrea Horváth, Tímea Csák, R. Zelkó

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Authors review the pathogenesis, symptoms and diagnosis of Wilson's disease. Wilson's disease or hepatolenticular degeneration is an autosomal recessive disorder. It is caused by defective hepatic excretion of copper. The disease is fatal without treatment. The prevention of severe permanent damage depends upon early recognition and diagnosis followed by appropriate lifelong anticopper treatment. The purpose of the therapy of Wilson's disease is to eliminate the copper by chelators (D-penicillamine, triethylene tetramine, ammonium tetrathiomolibdate) and to inhibit the absorption and accumulation of copper by zinc salts (zinc sulphate, zinc acetate, zinc gluconate).

Original languageHungarian
Pages (from-to)237-241
Number of pages5
JournalActa Pharmaceutica Hungarica
Volume73
Issue number4
Publication statusPublished - 2003

Fingerprint

Hepatolenticular Degeneration
Copper
tetramethylenedisulfotetramine
Zinc Acetate
Zinc Sulfate
Penicillamine
Chelating Agents
Ammonium Compounds
Zinc
Early Diagnosis
Salts
Therapeutics

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Nagy, J., Vincze, Z., Folhoffer, A., Horváth, A., Csák, T., & Zelkó, R. (2003). A Wilson-kór patomechanizmusa és gyógyszeres kezelése. Acta Pharmaceutica Hungarica, 73(4), 237-241.

A Wilson-kór patomechanizmusa és gyógyszeres kezelése. / Nagy, Judit; Vincze, Zoltán; Folhoffer, Anikó; Horváth, Andrea; Csák, Tímea; Zelkó, R.

In: Acta Pharmaceutica Hungarica, Vol. 73, No. 4, 2003, p. 237-241.

Research output: Contribution to journalArticle

Nagy, J, Vincze, Z, Folhoffer, A, Horváth, A, Csák, T & Zelkó, R 2003, 'A Wilson-kór patomechanizmusa és gyógyszeres kezelése', Acta Pharmaceutica Hungarica, vol. 73, no. 4, pp. 237-241.
Nagy J, Vincze Z, Folhoffer A, Horváth A, Csák T, Zelkó R. A Wilson-kór patomechanizmusa és gyógyszeres kezelése. Acta Pharmaceutica Hungarica. 2003;73(4):237-241.
Nagy, Judit ; Vincze, Zoltán ; Folhoffer, Anikó ; Horváth, Andrea ; Csák, Tímea ; Zelkó, R. / A Wilson-kór patomechanizmusa és gyógyszeres kezelése. In: Acta Pharmaceutica Hungarica. 2003 ; Vol. 73, No. 4. pp. 237-241.
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