A Wilson-kór patomechanizmusa és gyógyszeres kezelése

Translated title of the contribution: Pathogenesis and treatment of Wilson's disease

Judit Nagy, Zoltán Vincze, Anikó Folhoffer, Andrea Horváth, Tímea Csák, Romána Zelkó

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Authors review the pathogenesis, symptoms and diagnosis of Wilson's disease. Wilson's disease or hepatolenticular degeneration is an autosomal recessive disorder. It is caused by defective hepatic excretion of copper. The disease is fatal without treatment. The prevention of severe permanent damage depends upon early recognition and diagnosis followed by appropriate lifelong anticopper treatment. The purpose of the therapy of Wilson's disease is to eliminate the copper by chelators (D-penicillamine, triethylene tetramine, ammonium tetrathiomolibdate) and to inhibit the absorption and accumulation of copper by zinc salts (zinc sulphate, zinc acetate, zinc gluconate).

Original languageHungarian
Pages (from-to)237-241
Number of pages5
JournalActa pharmaceutica Hungarica
Volume73
Issue number4
Publication statusPublished - Dec 1 2003

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ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Nagy, J., Vincze, Z., Folhoffer, A., Horváth, A., Csák, T., & Zelkó, R. (2003). A Wilson-kór patomechanizmusa és gyógyszeres kezelése. Acta pharmaceutica Hungarica, 73(4), 237-241.