ParlS genome rearrangement server

I. Miklós, P. Ittzés, J. Hein

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Summary: ParlS Genome Rearrangement is a web server for a Bayesian analysis of unichromosomal genome pairs. The underlying model allows inversions, transpositions and inverted transpositions. The server generates a Markov chain using a Partial Importance Sampler technique, and samples trajectories of mutations from this chain. The user can specify several marginalizations to the posterior: the posterior distribution of number of mutations needed to transform one genome into another, length distribution of mutations, number of mutations that have occurred at a given site. Both text and graphical outputs are available. We provide a limited server, a downloadable unlimited server that can be installed locally on any linux/Unix operating system, and a database of mitochondrial gene orders.

Original languageEnglish
Pages (from-to)817-820
Number of pages4
JournalBioinformatics
Volume21
Issue number6
DOIs
Publication statusPublished - Mar 15 2005

Fingerprint

Genome Rearrangement
Mutation
Servers
Server
Genes
Genome
Transposition
Markov Chains
Gene Order
Mitochondrial Genes
Bayes Theorem
Computer operating systems
Web Server
Linux
Bayesian Analysis
Posterior distribution
Operating Systems
Markov processes
Markov chain
Inversion

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Computer Science Applications
  • Computational Theory and Mathematics

Cite this

ParlS genome rearrangement server. / Miklós, I.; Ittzés, P.; Hein, J.

In: Bioinformatics, Vol. 21, No. 6, 15.03.2005, p. 817-820.

Research output: Contribution to journalArticle

Miklós, I. ; Ittzés, P. ; Hein, J. / ParlS genome rearrangement server. In: Bioinformatics. 2005 ; Vol. 21, No. 6. pp. 817-820.
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