Parental smoking and children's respiratory health

Independent effects of prenatal and postnatal exposure

Sam Pattenden, Temenuga Antova, Manfred Neuberger, Bojidar Nikiforov, Manuela De Sario, Leticia Grize, Joachim Heinrich, Frantiska Hruba, Nicole Janssen, Heike Luttmann-Gibson, Larissa Privalova, P. Rudnai, Anna Splichalova, Renata Zlotkowska, Tony Fletcher

Research output: Contribution to journalArticle

156 Citations (Scopus)

Abstract

Objectives: Adverse effects have been reported of prenatal and/or postnatal passive exposure to smoking on children's health. Uncertainties remain about the relative importance of smoking at different periods in the child's life. We investigate this in a pooled analysis, on 53 879 children from 12 cross-sectional studies-components of the PATY study (Pollution And The Young). Methods: Effects were estimated, within each study, of three exposures: mother smoked during pregnancy, parental smoking in the first two years, current parental smoking. Outcomes were: wheeze, asthma, "woken by wheeze", bronchitis, nocturnal cough, morning cough, "sensitivity to inhaled allergens" and hay fever. Logistic regressions were used, controlling for individual risk factors and study area. Heterogeneity between study-specific results, and mean effects (allowing for heterogeneity) were estimated using meta-analytical tools. Results: There was strong evidence linking parental smoking to wheeze, asthma, bronchitis and nocturnal cough, with mean odds ratios all around 1.15, with independent effects of prenatal and postnatal exposures for most associations. Conclusions: Adverse effects of both pre- and postnatal parental smoking on children's respiratory health were confirmed. Asthma was most strongly associated with maternal smoking during pregnancy, but postnatal exposure showed independent associations with a range of other respiratory symptoms. All tobacco smoke exposure has serious consequences for children's respiratory health and needs to be reduced urgently.

Original languageEnglish
Pages (from-to)294-301
Number of pages8
JournalTobacco Control
Volume15
Issue number4
DOIs
Publication statusPublished - Aug 2006

Fingerprint

smoking
Smoking
health
Cough
Asthma
Bronchitis
pregnancy
Mothers
Pregnancy
Seasonal Allergic Rhinitis
Child Health
cross-sectional study
Smoke
Allergens
nicotine
Uncertainty
Tobacco
Cross-Sectional Studies
Logistic Models
logistics

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health Policy
  • Epidemiology

Cite this

Pattenden, S., Antova, T., Neuberger, M., Nikiforov, B., De Sario, M., Grize, L., ... Fletcher, T. (2006). Parental smoking and children's respiratory health: Independent effects of prenatal and postnatal exposure. Tobacco Control, 15(4), 294-301. https://doi.org/10.1136/tc.2005.015065

Parental smoking and children's respiratory health : Independent effects of prenatal and postnatal exposure. / Pattenden, Sam; Antova, Temenuga; Neuberger, Manfred; Nikiforov, Bojidar; De Sario, Manuela; Grize, Leticia; Heinrich, Joachim; Hruba, Frantiska; Janssen, Nicole; Luttmann-Gibson, Heike; Privalova, Larissa; Rudnai, P.; Splichalova, Anna; Zlotkowska, Renata; Fletcher, Tony.

In: Tobacco Control, Vol. 15, No. 4, 08.2006, p. 294-301.

Research output: Contribution to journalArticle

Pattenden, S, Antova, T, Neuberger, M, Nikiforov, B, De Sario, M, Grize, L, Heinrich, J, Hruba, F, Janssen, N, Luttmann-Gibson, H, Privalova, L, Rudnai, P, Splichalova, A, Zlotkowska, R & Fletcher, T 2006, 'Parental smoking and children's respiratory health: Independent effects of prenatal and postnatal exposure', Tobacco Control, vol. 15, no. 4, pp. 294-301. https://doi.org/10.1136/tc.2005.015065
Pattenden, Sam ; Antova, Temenuga ; Neuberger, Manfred ; Nikiforov, Bojidar ; De Sario, Manuela ; Grize, Leticia ; Heinrich, Joachim ; Hruba, Frantiska ; Janssen, Nicole ; Luttmann-Gibson, Heike ; Privalova, Larissa ; Rudnai, P. ; Splichalova, Anna ; Zlotkowska, Renata ; Fletcher, Tony. / Parental smoking and children's respiratory health : Independent effects of prenatal and postnatal exposure. In: Tobacco Control. 2006 ; Vol. 15, No. 4. pp. 294-301.
@article{545b5fa8f13242a69077d197a2d747f0,
title = "Parental smoking and children's respiratory health: Independent effects of prenatal and postnatal exposure",
abstract = "Objectives: Adverse effects have been reported of prenatal and/or postnatal passive exposure to smoking on children's health. Uncertainties remain about the relative importance of smoking at different periods in the child's life. We investigate this in a pooled analysis, on 53 879 children from 12 cross-sectional studies-components of the PATY study (Pollution And The Young). Methods: Effects were estimated, within each study, of three exposures: mother smoked during pregnancy, parental smoking in the first two years, current parental smoking. Outcomes were: wheeze, asthma, {"}woken by wheeze{"}, bronchitis, nocturnal cough, morning cough, {"}sensitivity to inhaled allergens{"} and hay fever. Logistic regressions were used, controlling for individual risk factors and study area. Heterogeneity between study-specific results, and mean effects (allowing for heterogeneity) were estimated using meta-analytical tools. Results: There was strong evidence linking parental smoking to wheeze, asthma, bronchitis and nocturnal cough, with mean odds ratios all around 1.15, with independent effects of prenatal and postnatal exposures for most associations. Conclusions: Adverse effects of both pre- and postnatal parental smoking on children's respiratory health were confirmed. Asthma was most strongly associated with maternal smoking during pregnancy, but postnatal exposure showed independent associations with a range of other respiratory symptoms. All tobacco smoke exposure has serious consequences for children's respiratory health and needs to be reduced urgently.",
author = "Sam Pattenden and Temenuga Antova and Manfred Neuberger and Bojidar Nikiforov and {De Sario}, Manuela and Leticia Grize and Joachim Heinrich and Frantiska Hruba and Nicole Janssen and Heike Luttmann-Gibson and Larissa Privalova and P. Rudnai and Anna Splichalova and Renata Zlotkowska and Tony Fletcher",
year = "2006",
month = "8",
doi = "10.1136/tc.2005.015065",
language = "English",
volume = "15",
pages = "294--301",
journal = "Tobacco Control",
issn = "0964-4563",
publisher = "BMJ Publishing Group",
number = "4",

}

TY - JOUR

T1 - Parental smoking and children's respiratory health

T2 - Independent effects of prenatal and postnatal exposure

AU - Pattenden, Sam

AU - Antova, Temenuga

AU - Neuberger, Manfred

AU - Nikiforov, Bojidar

AU - De Sario, Manuela

AU - Grize, Leticia

AU - Heinrich, Joachim

AU - Hruba, Frantiska

AU - Janssen, Nicole

AU - Luttmann-Gibson, Heike

AU - Privalova, Larissa

AU - Rudnai, P.

AU - Splichalova, Anna

AU - Zlotkowska, Renata

AU - Fletcher, Tony

PY - 2006/8

Y1 - 2006/8

N2 - Objectives: Adverse effects have been reported of prenatal and/or postnatal passive exposure to smoking on children's health. Uncertainties remain about the relative importance of smoking at different periods in the child's life. We investigate this in a pooled analysis, on 53 879 children from 12 cross-sectional studies-components of the PATY study (Pollution And The Young). Methods: Effects were estimated, within each study, of three exposures: mother smoked during pregnancy, parental smoking in the first two years, current parental smoking. Outcomes were: wheeze, asthma, "woken by wheeze", bronchitis, nocturnal cough, morning cough, "sensitivity to inhaled allergens" and hay fever. Logistic regressions were used, controlling for individual risk factors and study area. Heterogeneity between study-specific results, and mean effects (allowing for heterogeneity) were estimated using meta-analytical tools. Results: There was strong evidence linking parental smoking to wheeze, asthma, bronchitis and nocturnal cough, with mean odds ratios all around 1.15, with independent effects of prenatal and postnatal exposures for most associations. Conclusions: Adverse effects of both pre- and postnatal parental smoking on children's respiratory health were confirmed. Asthma was most strongly associated with maternal smoking during pregnancy, but postnatal exposure showed independent associations with a range of other respiratory symptoms. All tobacco smoke exposure has serious consequences for children's respiratory health and needs to be reduced urgently.

AB - Objectives: Adverse effects have been reported of prenatal and/or postnatal passive exposure to smoking on children's health. Uncertainties remain about the relative importance of smoking at different periods in the child's life. We investigate this in a pooled analysis, on 53 879 children from 12 cross-sectional studies-components of the PATY study (Pollution And The Young). Methods: Effects were estimated, within each study, of three exposures: mother smoked during pregnancy, parental smoking in the first two years, current parental smoking. Outcomes were: wheeze, asthma, "woken by wheeze", bronchitis, nocturnal cough, morning cough, "sensitivity to inhaled allergens" and hay fever. Logistic regressions were used, controlling for individual risk factors and study area. Heterogeneity between study-specific results, and mean effects (allowing for heterogeneity) were estimated using meta-analytical tools. Results: There was strong evidence linking parental smoking to wheeze, asthma, bronchitis and nocturnal cough, with mean odds ratios all around 1.15, with independent effects of prenatal and postnatal exposures for most associations. Conclusions: Adverse effects of both pre- and postnatal parental smoking on children's respiratory health were confirmed. Asthma was most strongly associated with maternal smoking during pregnancy, but postnatal exposure showed independent associations with a range of other respiratory symptoms. All tobacco smoke exposure has serious consequences for children's respiratory health and needs to be reduced urgently.

UR - http://www.scopus.com/inward/record.url?scp=33746866299&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33746866299&partnerID=8YFLogxK

U2 - 10.1136/tc.2005.015065

DO - 10.1136/tc.2005.015065

M3 - Article

VL - 15

SP - 294

EP - 301

JO - Tobacco Control

JF - Tobacco Control

SN - 0964-4563

IS - 4

ER -