Paraneoplastic syndrome in childhood

D. Schuler, R. Koos, I. Krauze, A. Peter

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The case of a 5 yr old boy is reported who at the age of 18 mth had successfully been operated upon for neuroblastoma and who had subsequently signs of cerebellar encephalopathy. The paraneoplastic conditions of childhood are discussed in connection with the reported case. Opsoclonus was not observed in the patient, and symptoms showed rapid improvement on methotrexate, carmustine and CCNU treatment. 6 mth later the child was free of neurological disturbances and only displayed a slight mental retardation (IQ : 88). Cytological alterations observed in the CSF during the cerebellar encephalopathy are described in detail. At present 41 mth after the operation the child is well and free of symptoms.

Original languageEnglish
Pages (from-to)31-40
Number of pages10
JournalActa Paediatrica Academiae Scientiarum Hungaricae
Volume18
Issue number1
Publication statusPublished - 1977

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Paraneoplastic Syndromes
Brain Diseases
Lomustine
Ocular Motility Disorders
Carmustine
Neuroblastoma
Methotrexate
Intellectual Disability
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Paraneoplastic syndrome in childhood. / Schuler, D.; Koos, R.; Krauze, I.; Peter, A.

In: Acta Paediatrica Academiae Scientiarum Hungaricae, Vol. 18, No. 1, 1977, p. 31-40.

Research output: Contribution to journalArticle

Schuler, D, Koos, R, Krauze, I & Peter, A 1977, 'Paraneoplastic syndrome in childhood', Acta Paediatrica Academiae Scientiarum Hungaricae, vol. 18, no. 1, pp. 31-40.
Schuler, D. ; Koos, R. ; Krauze, I. ; Peter, A. / Paraneoplastic syndrome in childhood. In: Acta Paediatrica Academiae Scientiarum Hungaricae. 1977 ; Vol. 18, No. 1. pp. 31-40.
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