Parameter optimization of H controller designed for tumor growth in the light of physiological aspects

Johanna Sapi, Daniel Andras Drexler, Levente Kovacs

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Citations (Scopus)

Abstract

According to the fact that cancer diseases are leading causes of death all around the world, development of cancer fighting therapies is necessary. Beside the medical knowledge, there is an extra need for engineering approach to solve this complex problem. The aim of this paper is to design controller for tumor growth under angiogenic inhibition, which on the one hand minimizes the input signal as far as possible (in order to have less side effects and greater cost-effectiveness) and on the other hand results in appropriately low tumor volume. Since the model contains uncertainties and measurement noise, the controller was designed using modern robust control methodology. Choosing of the ideal system and the weighting functions were done in the light of physiological aspects.

Original languageEnglish
Title of host publicationCINTI 2013 - 14th IEEE International Symposium on Computational Intelligence and Informatics, Proceedings
Pages19-24
Number of pages6
DOIs
Publication statusPublished - Dec 1 2013
Event14th IEEE International Symposium on Computational Intelligence and Informatics, CINTI 2013 - Budapest, Hungary
Duration: Nov 19 2013Nov 21 2013

Publication series

NameCINTI 2013 - 14th IEEE International Symposium on Computational Intelligence and Informatics, Proceedings

Other

Other14th IEEE International Symposium on Computational Intelligence and Informatics, CINTI 2013
CountryHungary
CityBudapest
Period11/19/1311/21/13

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ASJC Scopus subject areas

  • Artificial Intelligence
  • Information Systems

Cite this

Sapi, J., Drexler, D. A., & Kovacs, L. (2013). Parameter optimization of H controller designed for tumor growth in the light of physiological aspects. In CINTI 2013 - 14th IEEE International Symposium on Computational Intelligence and Informatics, Proceedings (pp. 19-24). [6705197] (CINTI 2013 - 14th IEEE International Symposium on Computational Intelligence and Informatics, Proceedings). https://doi.org/10.1109/CINTI.2013.6705197