Palladium catalyzed carbonylations of alkenyl halides with formic acid to get corresponding Α,Β-unsaturated carboxylic acids and esters

Brigitta Bartal, Gábor Mikle, L. Kollár, Péter Pongrácz

Research output: Contribution to journalArticle

Abstract

Palladium-catalysed carbonylation reactions have been developed in the presence of formic acid as carbon monoxide source. α,β-Unsaturated carboxylic acids and esters were synthesized by the transformation of alkenyl halides in moderate to good yields. The selection of the base proved to be crucial regarding the reaction outcome. A set of various substrates were proven under optimised reaction conditions. Compared to aliphatic alcohols, phenols showed excellent reactivity as O-nucleophiles.

Original languageEnglish
Pages (from-to)143-149
Number of pages7
JournalMolecular Catalysis
DOIs
Publication statusPublished - Apr 1 2019

Fingerprint

formic acid
Carbonylation
Nucleophiles
Phenols
Formic acid
Palladium
Carbon Monoxide
Carboxylic Acids
Carboxylic acids
carboxylic acids
Carbon monoxide
halides
palladium
esters
Esters
Alcohols
Substrates
nucleophiles
phenols
carbon monoxide

Keywords

  • Alkoxycarbonylation
  • Formic acid
  • Hydroxycarbonylation
  • Palladium

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology
  • Physical and Theoretical Chemistry

Cite this

Palladium catalyzed carbonylations of alkenyl halides with formic acid to get corresponding Α,Β-unsaturated carboxylic acids and esters. / Bartal, Brigitta; Mikle, Gábor; Kollár, L.; Pongrácz, Péter.

In: Molecular Catalysis, 01.04.2019, p. 143-149.

Research output: Contribution to journalArticle

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