PACAP and VIP in the photoneuroendocrine system (PNES)

Katalin Köves, Viktória Vereczki, Mária Kausz, Orsolya Kántor, Judith Molnár, Ágnes Nemeskéri, Andrea Heinzlmann, Enikö Szabó, Flóra Szabó, Kristóf Fógel, András Lakatos, Gábor Szeiffert, Akira Arimura

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The presence of PACAP and VIP was demonstrated in all the four levels of the photoneuroendocrine system (PNES) with the use of immunohistochemistry (IHC), radioimmunoassay (RIA), anterograde and retrograde tracing techniques, and cell immunoblot assay (CIBA). Both peptides play a physiological role in the PNES. According to our results both PACAP and VIP are involved in the regulation of the gonadotrop hormone secretion and their inhibitory role may be mediated through the neuronal chain of the PNES.

Original languageEnglish
Pages (from-to)SR5-SR20
JournalMedical Science Monitor
Issue number2
Publication statusPublished - Mar 23 2002


  • Gonadotrop hormone secretion
  • Immunohistochemistry
  • Photoneuroendocrine system (PNES)
  • Rat
  • Tracing techniques
  • VIP

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Köves, K., Vereczki, V., Kausz, M., Kántor, O., Molnár, J., Nemeskéri, Á., Heinzlmann, A., Szabó, E., Szabó, F., Fógel, K., Lakatos, A., Szeiffert, G., & Arimura, A. (2002). PACAP and VIP in the photoneuroendocrine system (PNES). Medical Science Monitor, 8(2), SR5-SR20.