P-082. Inhibition of microflora associated with implants in oral cancer patients

K. Nagy, I. Vajdovich, L. Borbély, I. Sonkodi, E. Urbán

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Osseointegrated implants placed into the microvascularised grafted bone, offers an opportunity for improved function and esthetical satisfaction of patients, subjected to radical excision surgery. Aim: To maintain peri-implant hygiene with elimination of occasional inflammation, to reduce patient morbidity. Methods: Ten patients, (eight male, two female, mean age: 53.6 years, S.D. = ±8.4; five dentate, five edentulous) were selected for this study, and all were previously diagnosed with oral, squamous cell carcinoma and had undergone major tumour operation. All patients had a minimum of two osseointegrated implants (DenTi) inserted. Submucosal plaque sample was obtained with a sterile paper point before and after rinsing with Meridol® solution for 7 days three times a day, and were transported in 1 ml reduced BHI broth to the microbiology laboratory, and commenced within 1 h of sampling. Results: Plaque accumulation and clinical periimplant inflammation were generally higher in partially dentate patients, rather than in the edentulous ones. The median number of colony forming units (CFU/ml) found in the peri-implant region before and after rinsing with Meridol® were compared. The total aerobic mean count varied from 7×102 to 7×105 and that for anaerobes from 7×102 to 3×106. Actinomyces, Prevotella Intermedia, Enterococcus faecalis, Porphyromonas gingivalis, were found in greater proportion at the clinically inflamed peri-implant site. Conclusion: We can state that rinsing with Meridol the total count of bacteria showed reduction for both aerobes and anaerobes, although numbers were not significant (P>0.05). Our results also indicate, that the gingival sulci of the remaining dentition may act as a reservoir from which bacteria seed to dental implants inserted into transplanted bone graft. This study was partly supported by GABA International Ltd, Switzerland and OTKA T029322.

Original languageEnglish
Pages (from-to)S79
JournalOral Oncology
Issue numberSUPPL. 1
Publication statusPublished - Dec 1 2001


ASJC Scopus subject areas

  • Oral Surgery
  • Oncology
  • Cancer Research

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