Oxidation of thiols to disulfides by dioxygen catalyzed by a bioinspired organocatalyst

Nárcisz Bagi, J. Kaizer, G. Speier

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

2,3-Dihydro-2,2,2-triphenylphenanthro[9,10-d]-1,3,2-λ5-oxazaphosphole serves as good catalyst for the oxidation of thiophenol, cysteine and glutathione to their disulfides by molecular oxygen. The kinetics of the reactions unveiled an overall second order rate equation for all reactions and pure dioxygen chemistry for all three substrates. The formation of an unstable hydroperoxide from the catalyst is assumed to be a key step during the reaction.

Original languageEnglish
Pages (from-to)45983-45986
Number of pages4
JournalRSC Advances
Volume5
Issue number57
DOIs
Publication statusPublished - 2015

Fingerprint

Sulfhydryl Compounds
Disulfides
Oxygen
Oxidation
Catalysts
Molecular oxygen
Hydrogen Peroxide
Glutathione
Cysteine
Kinetics
Substrates
thiophenol

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)

Cite this

Oxidation of thiols to disulfides by dioxygen catalyzed by a bioinspired organocatalyst. / Bagi, Nárcisz; Kaizer, J.; Speier, G.

In: RSC Advances, Vol. 5, No. 57, 2015, p. 45983-45986.

Research output: Contribution to journalArticle

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