Oxazolidin-2-one ring, a popular framework in synthetic organic chemistry

Part 1. The construction of the oxazolidin-2-one ring

G. Zappia, E. Gács-Baitz, G. Delle Monache, D. Misiti, L. Nevola, B. Botta

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

The 1,3-oxazolidin-2-one nucleus is a popular heterocycle framework in synthetic organic chemistry, as well as in medicinal chemistry. This paper deals with the huge number of synthetic approaches addressed to the construction of this five-member ring, with a particular care for the mechanistic and stereochemical outcome.

Original languageEnglish
Pages (from-to)81-135
Number of pages55
JournalCurrent Organic Synthesis
Volume4
Issue number1
DOIs
Publication statusPublished - Feb 2007

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Organic Chemistry
Oxazolidinones
Pharmaceutical Chemistry

Keywords

  • 1,2-aminoalcohol
  • 1,3-oxazolidin-2-one
  • Amino-acids
  • Curtius- rearrangement
  • Cyclocarbamation reactions
  • Epoxides and aziridines

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry

Cite this

Oxazolidin-2-one ring, a popular framework in synthetic organic chemistry : Part 1. The construction of the oxazolidin-2-one ring. / Zappia, G.; Gács-Baitz, E.; Delle Monache, G.; Misiti, D.; Nevola, L.; Botta, B.

In: Current Organic Synthesis, Vol. 4, No. 1, 02.2007, p. 81-135.

Research output: Contribution to journalArticle

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