Oxazepines and thiazepines 38 synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines by the reaction of 2′-hydroxychalcones with 2-aminothiophenol

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Abstract

Simple and convenient procedures have been developed for the synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines by the reaction of 2′-hydroxychalcones 1-22 with 2-aminothiophenol either in hot ethanol in the presence of piperidine or in hot toluene in the presence of trifluoroacetic acid.

Original languageEnglish
Pages (from-to)359-364
Number of pages6
JournalHeterocyclic Communications
Volume5
Issue number4
Publication statusPublished - 1999

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Thiazepines
Oxazepines
Trifluoroacetic Acid
Toluene
Ethanol
2'-hydroxychalcone
2-aminothiophenol
1,5-benzothiazepine
piperidine

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

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title = "Oxazepines and thiazepines 38 synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines by the reaction of 2′-hydroxychalcones with 2-aminothiophenol",
abstract = "Simple and convenient procedures have been developed for the synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines by the reaction of 2′-hydroxychalcones 1-22 with 2-aminothiophenol either in hot ethanol in the presence of piperidine or in hot toluene in the presence of trifluoroacetic acid.",
author = "A. L{\'e}vai",
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AB - Simple and convenient procedures have been developed for the synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines by the reaction of 2′-hydroxychalcones 1-22 with 2-aminothiophenol either in hot ethanol in the presence of piperidine or in hot toluene in the presence of trifluoroacetic acid.

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