Outbreak of septicaemic cases caused by Acinetobacter ursingii in a neonatal intensive care unit

Krisztina Máder, Gabriella Terhes, Edit Hajdú, E. Urbán, J. Sóki, Tibor Magyar, K. Márialigeti, M. Katona, E. Nagy, S. Túri

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Neonatal infections may be caused by various microorganisms, but as far as we are aware, Acinetobacter ursingii has not yet been reported in connection with nosocomial infections of premature infants. During 2 months, 3 premature babies were treated with nosocomial infection caused by A. ursingii at the same ward, and on the basis of molecular typing results the same strain was responsible for all of these cases. Traditional biochemical methods and automatic identification systems failed to identify this bacterium on the species level, and only 16S rDNA sequencing gave acceptable species identifications. The isolated strains proved to be susceptible to all of the tested antimicrobials, including ampicillin/sulbactam, doxycyclin, netilmicin, ciprofloxacin, piperacillin/tazobactam, ceftazidime, imipenem, meropenem, trimethoprim/sulfametoxazole, gentamicin, tobramycin, amikacin, and levofloxacin according to the CLSI standard. In spite of the environmental screening, the source of the infection could not be clarified. One of 3 neonates died, the others recovered and were discharged home after several months of hospitalization.

Original languageEnglish
Pages (from-to)338-340
Number of pages3
JournalInternational Journal of Medical Microbiology
Volume300
Issue number5
DOIs
Publication statusPublished - Jun 2010

Fingerprint

Acinetobacter
Neonatal Intensive Care Units
meropenem
Cross Infection
Disease Outbreaks
Netilmicin
Molecular Typing
Levofloxacin
Tobramycin
Trimethoprim
Ceftazidime
Amikacin
Imipenem
Ciprofloxacin
Ribosomal DNA
Infection
Gentamicins
Premature Infants
Hospitalization
Newborn Infant

Keywords

  • A. ursingii
  • Neonate
  • Nosocomial
  • Septicaemia

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases
  • Microbiology (medical)

Cite this

Outbreak of septicaemic cases caused by Acinetobacter ursingii in a neonatal intensive care unit. / Máder, Krisztina; Terhes, Gabriella; Hajdú, Edit; Urbán, E.; Sóki, J.; Magyar, Tibor; Márialigeti, K.; Katona, M.; Nagy, E.; Túri, S.

In: International Journal of Medical Microbiology, Vol. 300, No. 5, 06.2010, p. 338-340.

Research output: Contribution to journalArticle

@article{fa118b9ccf0040909979118227054541,
title = "Outbreak of septicaemic cases caused by Acinetobacter ursingii in a neonatal intensive care unit",
abstract = "Neonatal infections may be caused by various microorganisms, but as far as we are aware, Acinetobacter ursingii has not yet been reported in connection with nosocomial infections of premature infants. During 2 months, 3 premature babies were treated with nosocomial infection caused by A. ursingii at the same ward, and on the basis of molecular typing results the same strain was responsible for all of these cases. Traditional biochemical methods and automatic identification systems failed to identify this bacterium on the species level, and only 16S rDNA sequencing gave acceptable species identifications. The isolated strains proved to be susceptible to all of the tested antimicrobials, including ampicillin/sulbactam, doxycyclin, netilmicin, ciprofloxacin, piperacillin/tazobactam, ceftazidime, imipenem, meropenem, trimethoprim/sulfametoxazole, gentamicin, tobramycin, amikacin, and levofloxacin according to the CLSI standard. In spite of the environmental screening, the source of the infection could not be clarified. One of 3 neonates died, the others recovered and were discharged home after several months of hospitalization.",
keywords = "A. ursingii, Neonate, Nosocomial, Septicaemia",
author = "Krisztina M{\'a}der and Gabriella Terhes and Edit Hajd{\'u} and E. Urb{\'a}n and J. S{\'o}ki and Tibor Magyar and K. M{\'a}rialigeti and M. Katona and E. Nagy and S. T{\'u}ri",
year = "2010",
month = "6",
doi = "10.1016/j.ijmm.2009.10.007",
language = "English",
volume = "300",
pages = "338--340",
journal = "International Journal of Medical Microbiology",
issn = "1438-4221",
publisher = "Urban und Fischer Verlag GmbH und Co. KG",
number = "5",

}

TY - JOUR

T1 - Outbreak of septicaemic cases caused by Acinetobacter ursingii in a neonatal intensive care unit

AU - Máder, Krisztina

AU - Terhes, Gabriella

AU - Hajdú, Edit

AU - Urbán, E.

AU - Sóki, J.

AU - Magyar, Tibor

AU - Márialigeti, K.

AU - Katona, M.

AU - Nagy, E.

AU - Túri, S.

PY - 2010/6

Y1 - 2010/6

N2 - Neonatal infections may be caused by various microorganisms, but as far as we are aware, Acinetobacter ursingii has not yet been reported in connection with nosocomial infections of premature infants. During 2 months, 3 premature babies were treated with nosocomial infection caused by A. ursingii at the same ward, and on the basis of molecular typing results the same strain was responsible for all of these cases. Traditional biochemical methods and automatic identification systems failed to identify this bacterium on the species level, and only 16S rDNA sequencing gave acceptable species identifications. The isolated strains proved to be susceptible to all of the tested antimicrobials, including ampicillin/sulbactam, doxycyclin, netilmicin, ciprofloxacin, piperacillin/tazobactam, ceftazidime, imipenem, meropenem, trimethoprim/sulfametoxazole, gentamicin, tobramycin, amikacin, and levofloxacin according to the CLSI standard. In spite of the environmental screening, the source of the infection could not be clarified. One of 3 neonates died, the others recovered and were discharged home after several months of hospitalization.

AB - Neonatal infections may be caused by various microorganisms, but as far as we are aware, Acinetobacter ursingii has not yet been reported in connection with nosocomial infections of premature infants. During 2 months, 3 premature babies were treated with nosocomial infection caused by A. ursingii at the same ward, and on the basis of molecular typing results the same strain was responsible for all of these cases. Traditional biochemical methods and automatic identification systems failed to identify this bacterium on the species level, and only 16S rDNA sequencing gave acceptable species identifications. The isolated strains proved to be susceptible to all of the tested antimicrobials, including ampicillin/sulbactam, doxycyclin, netilmicin, ciprofloxacin, piperacillin/tazobactam, ceftazidime, imipenem, meropenem, trimethoprim/sulfametoxazole, gentamicin, tobramycin, amikacin, and levofloxacin according to the CLSI standard. In spite of the environmental screening, the source of the infection could not be clarified. One of 3 neonates died, the others recovered and were discharged home after several months of hospitalization.

KW - A. ursingii

KW - Neonate

KW - Nosocomial

KW - Septicaemia

UR - http://www.scopus.com/inward/record.url?scp=77952320077&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952320077&partnerID=8YFLogxK

U2 - 10.1016/j.ijmm.2009.10.007

DO - 10.1016/j.ijmm.2009.10.007

M3 - Article

VL - 300

SP - 338

EP - 340

JO - International Journal of Medical Microbiology

JF - International Journal of Medical Microbiology

SN - 1438-4221

IS - 5

ER -