A meddo férfiak spermiumainak citogenetikai vizsgálata elso hazai tapasztalatok

Translated title of the contribution: Our first experiences with cytogenetic investigations of sperms at infertile males

A. Tóth, Erika P. Tardy, Anna Kékesi, Sándor Drávucz, Zoltán Murányi, Miklós Vajda, István Dévai, Imre Cseh, Edit Erdei

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The purpose of this study was to analyze the rate of numerical chromosomal anomalies in sperm nuclei. Nine infertile patients and 25 control donors were evaluated for chromsomes 16, 18, X and Y. The infertile patients had normal karyotype but abnormal semen parameters. The mean rate of disomies was significantly higher in infertile males. In conclusion, patients with teratozoospermia or oligo-astheno-teratozoospermia may have an increased rate of sperm aneuploidy therefore a higher risk of producing genetically abnormal embryos. These findings suggest the necessity of genetic counselling before assisted reproductive techniques. Those patients who have high rate of chromosomal anomalies in sperms preimplantation or prenatal diagnosis should be considered. Future studies are needed to examine the aneuploidy rate for many of the remaining chromosomes and to decide the relationship between clinical phenotype and aneuploid frequency in sperm nuclei.

Original languageHungarian
Pages (from-to)143-147
Number of pages5
JournalMagyar Noorvosok Lapja
Volume66
Issue number3
Publication statusPublished - 2003

Fingerprint

Cytogenetics
Spermatozoa
Aneuploidy
Asthenozoospermia
Abnormal Karyotype
Preimplantation Diagnosis
Assisted Reproductive Techniques
Genetic Counseling
Semen
Prenatal Diagnosis
Embryonic Structures
Chromosomes
Tissue Donors
Phenotype

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Tóth, A., Tardy, E. P., Kékesi, A., Drávucz, S., Murányi, Z., Vajda, M., ... Erdei, E. (2003). A meddo férfiak spermiumainak citogenetikai vizsgálata elso hazai tapasztalatok. Magyar Noorvosok Lapja, 66(3), 143-147.

A meddo férfiak spermiumainak citogenetikai vizsgálata elso hazai tapasztalatok. / Tóth, A.; Tardy, Erika P.; Kékesi, Anna; Drávucz, Sándor; Murányi, Zoltán; Vajda, Miklós; Dévai, István; Cseh, Imre; Erdei, Edit.

In: Magyar Noorvosok Lapja, Vol. 66, No. 3, 2003, p. 143-147.

Research output: Contribution to journalArticle

Tóth, A, Tardy, EP, Kékesi, A, Drávucz, S, Murányi, Z, Vajda, M, Dévai, I, Cseh, I & Erdei, E 2003, 'A meddo férfiak spermiumainak citogenetikai vizsgálata elso hazai tapasztalatok', Magyar Noorvosok Lapja, vol. 66, no. 3, pp. 143-147.
Tóth A, Tardy EP, Kékesi A, Drávucz S, Murányi Z, Vajda M et al. A meddo férfiak spermiumainak citogenetikai vizsgálata elso hazai tapasztalatok. Magyar Noorvosok Lapja. 2003;66(3):143-147.
Tóth, A. ; Tardy, Erika P. ; Kékesi, Anna ; Drávucz, Sándor ; Murányi, Zoltán ; Vajda, Miklós ; Dévai, István ; Cseh, Imre ; Erdei, Edit. / A meddo férfiak spermiumainak citogenetikai vizsgálata elso hazai tapasztalatok. In: Magyar Noorvosok Lapja. 2003 ; Vol. 66, No. 3. pp. 143-147.
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