Osteoporotic fractures may impair life as much as the complications of diabetes

Z. Vokó, Katalin Gáspár, András Inotai, C. Horváth, Katalin Bors, G. Speer, Z. Kaló

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Rationale, aims, and objectives: To compare the effect of osteoporotic fractures and complications of diabetes mellitus on quality of life (QoL). Method: A cross-sectional study was performed in 840 patients with osteoporosis and in 943 patients with diabetes in Hungary to estimate the effect of osteoporotic fractures and microvascular and macrovascular complications of diabetes on QoL using the EQ-5D questionnaire. Ordinary least-squares regression was performed for the analysis to control for age and gender. Results: The effects of certain of osteoporotic fractures and diabetes complications were similar in size measured by the EQ-5D. Patients with hip fractures and compressions of the vertebrae suffered more than 0.2 drop in their QoL, which is comparable in size to the most severe complications of diabetes, such as vision loss and amputations. Conclusions: The use of mortality and premature mortality as the traditional measures of disease burden in public health policy making means that diseases which strongly affect QoL but less survival might not get the necessary priority. This is especially the case in low-income and middle-income countries where studies on QoL are scarce. Our comparative analysis, which showed that osteoporotic fractures reduce QoL as much as major complications of diabetes, highlights the need for comprehensive disease burden assessment, including losses in functionality and QoL, to support decision making.

Original languageEnglish
Pages (from-to)1375-1380
Number of pages6
JournalJournal of Evaluation in Clinical Practice
Volume23
Issue number6
DOIs
Publication statusPublished - Dec 1 2017

Fingerprint

Osteoporotic Fractures
Diabetes Complications
Quality of Life
Premature Mortality
Hungary
Policy Making
Hip Fractures
Public Policy
Health Policy
Least-Squares Analysis
Amputation
Osteoporosis
Decision Making
Spine
Public Health
Cross-Sectional Studies
Survival
Mortality

Keywords

  • diabetes mellitus
  • EuroQol-5D
  • fracture
  • osteoporosis
  • quality of life
  • utility

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Osteoporotic fractures may impair life as much as the complications of diabetes. / Vokó, Z.; Gáspár, Katalin; Inotai, András; Horváth, C.; Bors, Katalin; Speer, G.; Kaló, Z.

In: Journal of Evaluation in Clinical Practice, Vol. 23, No. 6, 01.12.2017, p. 1375-1380.

Research output: Contribution to journalArticle

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