Oscillations in plasma cortisol levels of newborns during exchange transfusion

E. Zoltan, J. Solyom

Research output: Contribution to journalArticle

Abstract

Plasma cortisol concentration was determined in blood samples obtained in six newborns during echange transfusion at 3-5 minute intervals. A radiotransin-assay using horse serum as a binding protein and toluene-based scintillation fluid for separation of unbound tracer proved to be a relatively specific method for determination of cortisol level in the plasma of newborns. Irregular oscillations were observed in four newborns, whereas a single peak could be demonstrated in two cases during the 40-70 minute period observed. The results suggest that the CRF-ACTH-cortisol secretion may already be episodic in the newborn period.

Original languageEnglish
Pages (from-to)335-340
Number of pages6
JournalEndokrinologie
Volume75
Issue number3
Publication statusPublished - Dec 1 1980

ASJC Scopus subject areas

  • Endocrinology

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