Organometallic polymeric carriers for redox triggered release of molecular payloads

Dominik Jańczewski, Jing Song, Erzsébet Csányi, Lóránd Kiss, Péter Blazsó, Róbert L. Katona, Mária A. Deli, Guillaume Gros, Jianwei Xu, G. Julius Vancso

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The synthesis and characterization of a novel redox responsive comb-copolymer consisting of a poly(ferrocenylsilane) backbone and N-dimethylethyl ammonium and N-dimethyldecyl ammonium substituents are reported. Due to the presence of the side groups featuring cationic amine as well as decyl hydrocarbon chains the comb copolymer exhibits amphiphilic behaviour and forms micellar assemblies with typical dimensions of 100 nm. The assemblies display unique, redox induced morphology change in water, investigated by dynamic light scattering and transmission electron microscopy. Paclitaxel and Nile Red were encapsulated in the micelles as model guest molecular payloads. Release of the guests with a high degree of profile control by varying the concentration of redox agents is presented.

Original languageEnglish
Pages (from-to)6429-6435
Number of pages7
JournalJournal of Materials Chemistry
Volume22
Issue number13
DOIs
Publication statusPublished - Apr 7 2012

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Organometallic polymeric carriers for redox triggered release of molecular payloads'. Together they form a unique fingerprint.

  • Cite this