Organometallic flavonoid derivatives as spectroscopic probes

Christopher E. Anson, Colin S. Creaser, J. Allan Downie, Orsolya Egyed, Andrej V. Malkov, Ljubica Mojovic, G. Richard Stephenson, Andrew T. Turner, Karen E. Wilson

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Derivatives of naringenin have been synthesized with organometalcarbonyl reporting groups for IR spectroscopy attached at C-2, C-3', or C-6, and the products have been tested for the induction of nod gene expression using a Rhizobium leguminosarum strain which contains the Escherichia coli lacZ (β- galactosidase) gene fused to nodABC. Derivatives with an OMe substituent within the reporting group moiety showed residual gene induction activity.

Original languageEnglish
Pages (from-to)3549-3554
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume8
Issue number24
DOIs
Publication statusPublished - Dec 15 1998

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Organometallic flavonoid derivatives as spectroscopic probes'. Together they form a unique fingerprint.

  • Cite this

    Anson, C. E., Creaser, C. S., Downie, J. A., Egyed, O., Malkov, A. V., Mojovic, L., Stephenson, G. R., Turner, A. T., & Wilson, K. E. (1998). Organometallic flavonoid derivatives as spectroscopic probes. Bioorganic and Medicinal Chemistry Letters, 8(24), 3549-3554. https://doi.org/10.1016/S0960-894X(98)00638-6