Optically active 1-(benzofuran-2-yl)ethanols and ethane-1,2-diols by enantiotopic selective bioreductions

Csaba Paizs, Monica Toşa, Cornelia Majdik, Paula Moldovan, L. Novák, P. Kolonits, Adriana Marcovici, Florin Dan Irimie, L. Poppe

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Enantiotopic selective reduction of 1-(benzofuran-2-yl)ethanones 1a-d, 1-(benzofuran-2-yl)-2-hydroxyethanones 4a-c and 2-acetoxy-1-(benzofuran-2-yl)ethanones 3a-c was performed by baker's yeast for preparation of optically active (benzofuran-2-yl)carbinols [(S)-5a-d, (S)-6a-c and (R)-6a-c, enantiomeric excess from 55 to 93% ee].

Original languageEnglish
Pages (from-to)1495-1501
Number of pages7
JournalTetrahedron Asymmetry
Volume14
Issue number11
DOIs
Publication statusPublished - Jun 6 2003

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Ethane
yeast
ethane
Yeast
Ethanol
ethyl alcohol
preparation
Methanol
Saccharomyces cerevisiae
1-benzofuran

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Organic Chemistry
  • Materials Chemistry
  • Drug Discovery

Cite this

Optically active 1-(benzofuran-2-yl)ethanols and ethane-1,2-diols by enantiotopic selective bioreductions. / Paizs, Csaba; Toşa, Monica; Majdik, Cornelia; Moldovan, Paula; Novák, L.; Kolonits, P.; Marcovici, Adriana; Irimie, Florin Dan; Poppe, L.

In: Tetrahedron Asymmetry, Vol. 14, No. 11, 06.06.2003, p. 1495-1501.

Research output: Contribution to journalArticle

Paizs, Csaba ; Toşa, Monica ; Majdik, Cornelia ; Moldovan, Paula ; Novák, L. ; Kolonits, P. ; Marcovici, Adriana ; Irimie, Florin Dan ; Poppe, L. / Optically active 1-(benzofuran-2-yl)ethanols and ethane-1,2-diols by enantiotopic selective bioreductions. In: Tetrahedron Asymmetry. 2003 ; Vol. 14, No. 11. pp. 1495-1501.
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