Optical resolution of 2-(3-chloro-phenyl)-3,4A, 5,6,7,7A- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in water-chloroform two phase solvent system

Dávid Kozma, G. Egri, E. Fogassy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Optical resolution of racemic 2-(3-chloro-phenyl)-3,4a,5,6,7,7a- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in an unusual solvent combination, in water-chloroform two phase solvent system was accomplished. During enantiomeric enrichment of the resulted raw base the optically active base can be recovered from the ethanolic mother liquor.

Original languageEnglish
Pages (from-to)2265-2270
Number of pages6
JournalSynthetic Communications
Volume29
Issue number13
Publication statusPublished - 1999

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Chloroform
Water
tartaric acid

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

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title = "Optical resolution of 2-(3-chloro-phenyl)-3,4A, 5,6,7,7A- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in water-chloroform two phase solvent system",
abstract = "Optical resolution of racemic 2-(3-chloro-phenyl)-3,4a,5,6,7,7a- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in an unusual solvent combination, in water-chloroform two phase solvent system was accomplished. During enantiomeric enrichment of the resulted raw base the optically active base can be recovered from the ethanolic mother liquor.",
author = "D{\'a}vid Kozma and G. Egri and E. Fogassy",
year = "1999",
language = "English",
volume = "29",
pages = "2265--2270",
journal = "Synthetic Communications",
issn = "0039-7911",
publisher = "Taylor and Francis Ltd.",
number = "13",

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TY - JOUR

T1 - Optical resolution of 2-(3-chloro-phenyl)-3,4A, 5,6,7,7A- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in water-chloroform two phase solvent system

AU - Kozma, Dávid

AU - Egri, G.

AU - Fogassy, E.

PY - 1999

Y1 - 1999

N2 - Optical resolution of racemic 2-(3-chloro-phenyl)-3,4a,5,6,7,7a- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in an unusual solvent combination, in water-chloroform two phase solvent system was accomplished. During enantiomeric enrichment of the resulted raw base the optically active base can be recovered from the ethanolic mother liquor.

AB - Optical resolution of racemic 2-(3-chloro-phenyl)-3,4a,5,6,7,7a- hexahydrocyclopentapyrimidin-4-one with O,O'-dibenzoyl-2R,3R-tartaric acid in an unusual solvent combination, in water-chloroform two phase solvent system was accomplished. During enantiomeric enrichment of the resulted raw base the optically active base can be recovered from the ethanolic mother liquor.

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AN - SCOPUS:0032915777

VL - 29

SP - 2265

EP - 2270

JO - Synthetic Communications

JF - Synthetic Communications

SN - 0039-7911

IS - 13

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