Opposite short-term changes induced by an organophosphate in cortical and hippocampal evoked activity

A. Papp, K. Gyorgyi, L. Nagyrmajtenyi, I. Dési

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Organophosphates are the most widely used pesticides throughout the world. The considerable amount brought out to the environment poses a risk on the whole population. As organophosphates are neurotoxic substances and their residues can persist in the environment for several weeks, their influence on the nervous system of humans and animals is of principal interest. In the present study, we investigated the alterations induced by dichlorvos, a common pesticide substance, in parameters of somatosensory evoked potentials and hippocampal evoked population spikes of rats. The changes of the conical vs. hippocampal evoked responses were opposite and only hippocampal effects could be directly explained through an increased cholinergic activity.

Original languageEnglish
Pages (from-to)431-440
Number of pages10
JournalNeurobiology
Volume4
Issue number4
Publication statusPublished - 1996

Fingerprint

Organophosphates
Pesticides
Dichlorvos
Somatosensory Evoked Potentials
Cholinergic Agents
Nervous System
Population

Keywords

  • Cholinergic system
  • Cortical evoked potential
  • Hippocampal population spike
  • Organophosphate
  • Rat

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Opposite short-term changes induced by an organophosphate in cortical and hippocampal evoked activity. / Papp, A.; Gyorgyi, K.; Nagyrmajtenyi, L.; Dési, I.

In: Neurobiology, Vol. 4, No. 4, 1996, p. 431-440.

Research output: Contribution to journalArticle

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