Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes

L. Roewer, M. Krawczak, S. Willuweit, M. Nagy, C. Alves, A. Amorim, K. Anslinger, C. Augustin, A. Betz, E. Bosch, A. Cagliá, A. Carracedo, D. Corach, A. F. Dekairelle, T. Dobosz, B. M. Dupuy, S. Füredi, C. Gehrig, L. Gusmaõ, J. HenkeL. Henke, M. Hidding, C. Hohoff, B. Hoste, M. A. Jobling, H. J. Kärgel, P. De Knijff, R. Lessig, E. Liebeherr, M. Lorente, B. Martínez-Jarreta, P. Nievas, M. Nowak, W. Parson, V. L. Pascali, G. Penacino, R. Ploski, B. Rolf, A. Sala, U. Schmidt, C. Schmitt, P. M. Schneider, R. Szibor, J. Teifel-Greding, M. Kayser

Research output: Contribution to journalArticle

178 Citations (Scopus)

Abstract

The reference database of highly informative Y-chromosomal short tandem repeat (STR) haplotypes (YHRD), available online at http://ystr.charite.de, represents the largest collection of male-specific genetic profiles currently available for European populations. By September 2000, YHRD contained 4688 9-locus (so-called 'minimal') haplotypes, 40% of which have been extended further to include two additional loci. Establishment of YHRD has been facilitated by the joint efforts of 31 forensic and anthropological institutions. All contributing laboratories have agreed to standardize their Y-STR haplotyping protocols and to participate in a quality assurance exercise prior to the inclusion of any data. In view of its collaborative character, and in order to put YHRD to its intended use, viz. the support of forensic caseworkers in their routine decision-making process, the database has been made publicly available via the Internet in February 2000. Online searches for complete or partial Y-STR haplotypes from evidentiary or non-probative material can be performed on a non-commercial basis, and yield observed haplotype counts as well as extrapolated population frequency estimates. In addition, the YHRD website provides information about the quality control test, genotyping protocols, haplotype formats and informativity, population genetic analysis, literature references, and a list of contact addresses of the contributing laboratories.

Original languageEnglish
Pages (from-to)106-113
Number of pages8
JournalForensic Science International
Volume118
Issue number2-3
DOIs
Publication statusPublished - May 15 2001

Fingerprint

Microsatellite Repeats
Haplotypes
Databases
Network protocols
Quality assurance
Quality control
Websites
Decision making
Internet
Anthropology
Population Genetics
Quality Control
Population
Decision Making

Keywords

  • Database
  • Forensics
  • Haplotype
  • STR
  • Y chromosome

ASJC Scopus subject areas

  • Genetics
  • Analytical Chemistry
  • Pathology and Forensic Medicine
  • Psychiatry and Mental health

Cite this

Roewer, L., Krawczak, M., Willuweit, S., Nagy, M., Alves, C., Amorim, A., ... Kayser, M. (2001). Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes. Forensic Science International, 118(2-3), 106-113. https://doi.org/10.1016/S0379-0738(00)00478-3

Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes. / Roewer, L.; Krawczak, M.; Willuweit, S.; Nagy, M.; Alves, C.; Amorim, A.; Anslinger, K.; Augustin, C.; Betz, A.; Bosch, E.; Cagliá, A.; Carracedo, A.; Corach, D.; Dekairelle, A. F.; Dobosz, T.; Dupuy, B. M.; Füredi, S.; Gehrig, C.; Gusmaõ, L.; Henke, J.; Henke, L.; Hidding, M.; Hohoff, C.; Hoste, B.; Jobling, M. A.; Kärgel, H. J.; De Knijff, P.; Lessig, R.; Liebeherr, E.; Lorente, M.; Martínez-Jarreta, B.; Nievas, P.; Nowak, M.; Parson, W.; Pascali, V. L.; Penacino, G.; Ploski, R.; Rolf, B.; Sala, A.; Schmidt, U.; Schmitt, C.; Schneider, P. M.; Szibor, R.; Teifel-Greding, J.; Kayser, M.

In: Forensic Science International, Vol. 118, No. 2-3, 15.05.2001, p. 106-113.

Research output: Contribution to journalArticle

Roewer, L, Krawczak, M, Willuweit, S, Nagy, M, Alves, C, Amorim, A, Anslinger, K, Augustin, C, Betz, A, Bosch, E, Cagliá, A, Carracedo, A, Corach, D, Dekairelle, AF, Dobosz, T, Dupuy, BM, Füredi, S, Gehrig, C, Gusmaõ, L, Henke, J, Henke, L, Hidding, M, Hohoff, C, Hoste, B, Jobling, MA, Kärgel, HJ, De Knijff, P, Lessig, R, Liebeherr, E, Lorente, M, Martínez-Jarreta, B, Nievas, P, Nowak, M, Parson, W, Pascali, VL, Penacino, G, Ploski, R, Rolf, B, Sala, A, Schmidt, U, Schmitt, C, Schneider, PM, Szibor, R, Teifel-Greding, J & Kayser, M 2001, 'Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes', Forensic Science International, vol. 118, no. 2-3, pp. 106-113. https://doi.org/10.1016/S0379-0738(00)00478-3
Roewer, L. ; Krawczak, M. ; Willuweit, S. ; Nagy, M. ; Alves, C. ; Amorim, A. ; Anslinger, K. ; Augustin, C. ; Betz, A. ; Bosch, E. ; Cagliá, A. ; Carracedo, A. ; Corach, D. ; Dekairelle, A. F. ; Dobosz, T. ; Dupuy, B. M. ; Füredi, S. ; Gehrig, C. ; Gusmaõ, L. ; Henke, J. ; Henke, L. ; Hidding, M. ; Hohoff, C. ; Hoste, B. ; Jobling, M. A. ; Kärgel, H. J. ; De Knijff, P. ; Lessig, R. ; Liebeherr, E. ; Lorente, M. ; Martínez-Jarreta, B. ; Nievas, P. ; Nowak, M. ; Parson, W. ; Pascali, V. L. ; Penacino, G. ; Ploski, R. ; Rolf, B. ; Sala, A. ; Schmidt, U. ; Schmitt, C. ; Schneider, P. M. ; Szibor, R. ; Teifel-Greding, J. ; Kayser, M. / Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes. In: Forensic Science International. 2001 ; Vol. 118, No. 2-3. pp. 106-113.
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AU - Alves, C.

AU - Amorim, A.

AU - Anslinger, K.

AU - Augustin, C.

AU - Betz, A.

AU - Bosch, E.

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AU - Kärgel, H. J.

AU - De Knijff, P.

AU - Lessig, R.

AU - Liebeherr, E.

AU - Lorente, M.

AU - Martínez-Jarreta, B.

AU - Nievas, P.

AU - Nowak, M.

AU - Parson, W.

AU - Pascali, V. L.

AU - Penacino, G.

AU - Ploski, R.

AU - Rolf, B.

AU - Sala, A.

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