One-and-a-half syndrome--two cases.

Sándor Ilniczky, Anita Kamondi, György Várallyay, Barbara Gaal, Agnes Palásti, Szilvia Gulyás, Imre Szirmai

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4 Citations (Scopus)


One-and-a-half syndrome is characterized by combination of the clinical features of unilateral horizontal gaze palsy and internuclear ophthalmoplegia. The common symptoms are double vision and oscillopsia. The lesion is located in the paramedian pontine reticular formation, involving the centre of horizontal gaze and medial longitudinal fasciculus. More extensive brainstem damage may result in additional neurological signs. The most frequent underlying diseases are vascular insults, multiple sclerosis, and brainstem tumor. We present two cases of one-and-a-half syndrome. Both patients had lacunar infarction in the paramedian pontine tegmentum, revealed by MRI. The first patient had isolated eye movement disorder, while the second had additional nuclear-type facial paresis. In the first case brainstem evoked potentials indicated brainstem damage, in the second patient it was normal. Ocular symptoms improved within some days in both patients.

Original languageEnglish
Pages (from-to)489-493
Number of pages5
JournalIdeggyógyászati szemle
Issue number11-12
Publication statusPublished - Nov 30 2007

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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  • Cite this

    Ilniczky, S., Kamondi, A., Várallyay, G., Gaal, B., Palásti, A., Gulyás, S., & Szirmai, I. (2007). One-and-a-half syndrome--two cases. Ideggyógyászati szemle, 60(11-12), 489-493.