Onkogének és tumor szuppresszor gének a növekedési faktorok jelátvivö pályáiban.

Translated title of the contribution: Oncogenes and tumor suppressor genes in the signal transduction pathways of growth factors

Research output: Contribution to journalArticle

Abstract

Growth factors, such as insulin, EGF, PDGF, are indispensable elements of the regulation of cell proliferation. In the last years signal transduction pathways of many growth factors have been elucidated. p21 ras, a proto-oncogene product, plays a central role in growth signalling. The medical importance of the investigation of Ras proteins comes from the fact that mutant forms of Ras genes were found in a number of human tumours. The review summarizes the signal transduction pathways of growth factors, with special respect to the connection of protooncogenes, tumour suppressor genes and cancer research.

Original languageHungarian
Pages (from-to)2579-2584
Number of pages6
JournalOrvosi Hetilap
Volume135
Issue number47
Publication statusPublished - Nov 20 1994

Fingerprint

Tumor Suppressor Genes
Oncogenes
Signal Transduction
Intercellular Signaling Peptides and Proteins
Proto-Oncogene Proteins p21(ras)
ras Proteins
ras Genes
Epidermal Growth Factor
Neoplasms
Cell Proliferation
Insulin
Growth
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Onkogének és tumor szuppresszor gének a növekedési faktorok jelátvivö pályáiban. / Buday, L.

In: Orvosi Hetilap, Vol. 135, No. 47, 20.11.1994, p. 2579-2584.

Research output: Contribution to journalArticle

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