ZUR POLYMORPHIE DER BARBITURATE IN PULVERN UND TABLETTEN. IV. MITTEILUNG

AUFLOSUNG VON BARBITAL B UND A (MODIFIKATION I UND III) UND DEREN FREISETZUNG AUS TABLETTEN

Translated title of the contribution: On the polymorphism of barbiturates in powders and tablets. Part IV. The dissolution of barbital B and barbital A (modifications I and III) and their release from tablets

K. Hollenbach, K. Pintye-Hódi, G. Kedvessy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Two commerical brands of barbital (A: German Democratic Republic, modification III; B: Hungarian People's Republic, modification I) were used to study the solubility and dissolution of the modifications. Crystals of these two substances were brought into the shape of tablets, the physical parameters and textural properties of which were determined. The effect of polymorphism on the release of these substances is discussed in the light of the results obtained from this investigation.

Original languageGerman
Pages (from-to)32-35
Number of pages4
JournalPharmazie
Volume35
Issue number1
Publication statusPublished - 1980

Fingerprint

Barbital
East Germany
Barbiturates
Polymorphism
Powders
Solubility
Tablets
Dissolution
Crystals

ASJC Scopus subject areas

  • Molecular Medicine
  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science
  • Pharmacology

Cite this

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abstract = "Two commerical brands of barbital (A: German Democratic Republic, modification III; B: Hungarian People's Republic, modification I) were used to study the solubility and dissolution of the modifications. Crystals of these two substances were brought into the shape of tablets, the physical parameters and textural properties of which were determined. The effect of polymorphism on the release of these substances is discussed in the light of the results obtained from this investigation.",
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AU - Pintye-Hódi, K.

AU - Kedvessy, G.

PY - 1980

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N2 - Two commerical brands of barbital (A: German Democratic Republic, modification III; B: Hungarian People's Republic, modification I) were used to study the solubility and dissolution of the modifications. Crystals of these two substances were brought into the shape of tablets, the physical parameters and textural properties of which were determined. The effect of polymorphism on the release of these substances is discussed in the light of the results obtained from this investigation.

AB - Two commerical brands of barbital (A: German Democratic Republic, modification III; B: Hungarian People's Republic, modification I) were used to study the solubility and dissolution of the modifications. Crystals of these two substances were brought into the shape of tablets, the physical parameters and textural properties of which were determined. The effect of polymorphism on the release of these substances is discussed in the light of the results obtained from this investigation.

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