On the ontogenesis of the hypothalamic luteinizing hormone-releasing hormone /LH-RH/ in the male and female rat

T. Wenger, A. Nemeskeri

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Abstract

The LH-RH content of the developing hypothalamus of male and female rats from day 15 of fetal life up to postnatal day 42 in males and up to the day of vaginal opening in females was assessed by RIA. The neurohormone could first be detected in the hypothalami of 17 day old fetuses of both sexes. From 25th postnatal day the LH-RH content of the female medio-basal hypothalamus significantly exceeds that of the male. With regard to the anterior hypothalamus, from day 35 to the day of vaginal opening there is a more pronounced increase in the LH-RH of the anterior hypothalamus of the female as compared to the male. The results are consistent with the view that the anterior hypothalamus might be involved in the control of puberty of the female rat.

Original languageEnglish
Pages (from-to)29-34
Number of pages6
JournalNeuroendocrinology Letters
Volume1
Issue number1
Publication statusPublished - Jan 1 1979

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ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Neurology
  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Psychiatry and Mental health

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