On the mechanism of renal sodium handling in newborn infants

E. Sulyok, F. Varga, E. Gyory

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Citations (Scopus)

Abstract

In an attempt to delineate the specific tubular defect in sodium reabsorption in low-birth-weight neonates, fractional sodium excretion [C(Na)/C(Cr)], distal tubular sodium delivery [C(Na)+C(H2O)], and distal tubular sodium reabsorption [C(H2O)/C(H2O)+C(Na)] X 100) were determined in 8 healthy premature and 10 full-term newborn infants. The mean birth weight was 1,701 g (range: 1,240-2,120 g) and the mean gestational age was 32.6 weeks (range: 28-35 weeks) for premature; and 3,199 g (range: 2,670-3,670 g) and 38.9 weeks (range: 38-41 weeks) for full-term neonates. It was demonstrated that the significantly higher fractional sodium excretion in premature infants (1.44 ± 0.33 SE versus 0.36 ± 0.09%, p <0.01) resulted from significantly decreased proximal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 0.105 versus 0.360 ± 0.069 ml/min/1.73 m2, p <0.05] and distal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 3.3 versus 85.8 ± 3.4%, p <0.01) tubular sodium reabsorption.

Original languageEnglish
Title of host publicationBIOL. NEONATE
Pages75-79
Number of pages5
Volume37
Edition1-2
Publication statusPublished - 1980

Fingerprint

Sodium
Newborn Infant
Kidney
Low Birth Weight Infant
Birth Weight
Premature Infants
Gestational Age

ASJC Scopus subject areas

  • Medicine(all)
  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Sulyok, E., Varga, F., & Gyory, E. (1980). On the mechanism of renal sodium handling in newborn infants. In BIOL. NEONATE (1-2 ed., Vol. 37, pp. 75-79)

On the mechanism of renal sodium handling in newborn infants. / Sulyok, E.; Varga, F.; Gyory, E.

BIOL. NEONATE. Vol. 37 1-2. ed. 1980. p. 75-79.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sulyok, E, Varga, F & Gyory, E 1980, On the mechanism of renal sodium handling in newborn infants. in BIOL. NEONATE. 1-2 edn, vol. 37, pp. 75-79.
Sulyok E, Varga F, Gyory E. On the mechanism of renal sodium handling in newborn infants. In BIOL. NEONATE. 1-2 ed. Vol. 37. 1980. p. 75-79
Sulyok, E. ; Varga, F. ; Gyory, E. / On the mechanism of renal sodium handling in newborn infants. BIOL. NEONATE. Vol. 37 1-2. ed. 1980. pp. 75-79
@inbook{6f691a76174147f88c23c1e90dcf59a6,
title = "On the mechanism of renal sodium handling in newborn infants",
abstract = "In an attempt to delineate the specific tubular defect in sodium reabsorption in low-birth-weight neonates, fractional sodium excretion [C(Na)/C(Cr)], distal tubular sodium delivery [C(Na)+C(H2O)], and distal tubular sodium reabsorption [C(H2O)/C(H2O)+C(Na)] X 100) were determined in 8 healthy premature and 10 full-term newborn infants. The mean birth weight was 1,701 g (range: 1,240-2,120 g) and the mean gestational age was 32.6 weeks (range: 28-35 weeks) for premature; and 3,199 g (range: 2,670-3,670 g) and 38.9 weeks (range: 38-41 weeks) for full-term neonates. It was demonstrated that the significantly higher fractional sodium excretion in premature infants (1.44 ± 0.33 SE versus 0.36 ± 0.09{\%}, p <0.01) resulted from significantly decreased proximal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 0.105 versus 0.360 ± 0.069 ml/min/1.73 m2, p <0.05] and distal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 3.3 versus 85.8 ± 3.4{\%}, p <0.01) tubular sodium reabsorption.",
author = "E. Sulyok and F. Varga and E. Gyory",
year = "1980",
language = "English",
volume = "37",
pages = "75--79",
booktitle = "BIOL. NEONATE",
edition = "1-2",

}

TY - CHAP

T1 - On the mechanism of renal sodium handling in newborn infants

AU - Sulyok, E.

AU - Varga, F.

AU - Gyory, E.

PY - 1980

Y1 - 1980

N2 - In an attempt to delineate the specific tubular defect in sodium reabsorption in low-birth-weight neonates, fractional sodium excretion [C(Na)/C(Cr)], distal tubular sodium delivery [C(Na)+C(H2O)], and distal tubular sodium reabsorption [C(H2O)/C(H2O)+C(Na)] X 100) were determined in 8 healthy premature and 10 full-term newborn infants. The mean birth weight was 1,701 g (range: 1,240-2,120 g) and the mean gestational age was 32.6 weeks (range: 28-35 weeks) for premature; and 3,199 g (range: 2,670-3,670 g) and 38.9 weeks (range: 38-41 weeks) for full-term neonates. It was demonstrated that the significantly higher fractional sodium excretion in premature infants (1.44 ± 0.33 SE versus 0.36 ± 0.09%, p <0.01) resulted from significantly decreased proximal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 0.105 versus 0.360 ± 0.069 ml/min/1.73 m2, p <0.05] and distal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 3.3 versus 85.8 ± 3.4%, p <0.01) tubular sodium reabsorption.

AB - In an attempt to delineate the specific tubular defect in sodium reabsorption in low-birth-weight neonates, fractional sodium excretion [C(Na)/C(Cr)], distal tubular sodium delivery [C(Na)+C(H2O)], and distal tubular sodium reabsorption [C(H2O)/C(H2O)+C(Na)] X 100) were determined in 8 healthy premature and 10 full-term newborn infants. The mean birth weight was 1,701 g (range: 1,240-2,120 g) and the mean gestational age was 32.6 weeks (range: 28-35 weeks) for premature; and 3,199 g (range: 2,670-3,670 g) and 38.9 weeks (range: 38-41 weeks) for full-term neonates. It was demonstrated that the significantly higher fractional sodium excretion in premature infants (1.44 ± 0.33 SE versus 0.36 ± 0.09%, p <0.01) resulted from significantly decreased proximal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 0.105 versus 0.360 ± 0.069 ml/min/1.73 m2, p <0.05] and distal ([C(H2O)/H2O)+C(Na)] X 100:69.9 ± 3.3 versus 85.8 ± 3.4%, p <0.01) tubular sodium reabsorption.

UR - http://www.scopus.com/inward/record.url?scp=0018908363&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018908363&partnerID=8YFLogxK

M3 - Chapter

VL - 37

SP - 75

EP - 79

BT - BIOL. NEONATE

ER -