On the applicability and performance of the single particle ICP-MS nano-dispersion characterization method in cases complicated by spectral interferences

Ildikó Kálomista, Albert Kéri, G. Galbács

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In the present study, the applicability of single particle inductively coupled plasma mass spectroscopy (SP-ICP-MS) to the characterization of nano-dispersions is investigated in cases when the measurements are complicated by isobaric or polyatomic interferences. The specific classes of problems associated with spectral interferences in SP-ICP-MS measurements are described and the ways potentially applicable to the mitigation of these are discussed. Detailed experimental data are presented for the dispersions of Fe2O3, Cr2O3 and ZnO nanoparticles (NPs) stabilized with polyacrylic acid. The analytical performance of helium collision cell SP-ICP-MS was also assessed in detail. Although the sensitivity of the measurement for medium or low mass analytes decreased when the collision cell was used, the repeatability of the signal remained surprisingly good (3-6% RSD) even when NP signals were less than 50 counts and the acquisition time was kept as low as 100 s. In the helium mode, the size detection limit values were found to be 39 nm for Cr2O3, 15 nm for Fe2O3, 20 nm for ZnO and 35 nm for Ag NPs. These values are only 10-15% larger than comparable values found in no gas mode.

Original languageEnglish
Pages (from-to)1112-1122
Number of pages11
JournalJournal of Analytical Atomic Spectrometry
Volume31
Issue number5
DOIs
Publication statusPublished - May 1 2016

Fingerprint

Inductively coupled plasma
Helium
carbopol 940
Spectroscopy
Nanoparticles
Dispersions
Gases

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

@article{2eb81bb136d240b4bf00c7238707015b,
title = "On the applicability and performance of the single particle ICP-MS nano-dispersion characterization method in cases complicated by spectral interferences",
abstract = "In the present study, the applicability of single particle inductively coupled plasma mass spectroscopy (SP-ICP-MS) to the characterization of nano-dispersions is investigated in cases when the measurements are complicated by isobaric or polyatomic interferences. The specific classes of problems associated with spectral interferences in SP-ICP-MS measurements are described and the ways potentially applicable to the mitigation of these are discussed. Detailed experimental data are presented for the dispersions of Fe2O3, Cr2O3 and ZnO nanoparticles (NPs) stabilized with polyacrylic acid. The analytical performance of helium collision cell SP-ICP-MS was also assessed in detail. Although the sensitivity of the measurement for medium or low mass analytes decreased when the collision cell was used, the repeatability of the signal remained surprisingly good (3-6{\%} RSD) even when NP signals were less than 50 counts and the acquisition time was kept as low as 100 s. In the helium mode, the size detection limit values were found to be 39 nm for Cr2O3, 15 nm for Fe2O3, 20 nm for ZnO and 35 nm for Ag NPs. These values are only 10-15{\%} larger than comparable values found in no gas mode.",
author = "Ildik{\'o} K{\'a}lomista and Albert K{\'e}ri and G. Galb{\'a}cs",
year = "2016",
month = "5",
day = "1",
doi = "10.1039/c5ja00501a",
language = "English",
volume = "31",
pages = "1112--1122",
journal = "Journal of Analytical Atomic Spectrometry",
issn = "0267-9477",
publisher = "Royal Society of Chemistry",
number = "5",

}

TY - JOUR

T1 - On the applicability and performance of the single particle ICP-MS nano-dispersion characterization method in cases complicated by spectral interferences

AU - Kálomista, Ildikó

AU - Kéri, Albert

AU - Galbács, G.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - In the present study, the applicability of single particle inductively coupled plasma mass spectroscopy (SP-ICP-MS) to the characterization of nano-dispersions is investigated in cases when the measurements are complicated by isobaric or polyatomic interferences. The specific classes of problems associated with spectral interferences in SP-ICP-MS measurements are described and the ways potentially applicable to the mitigation of these are discussed. Detailed experimental data are presented for the dispersions of Fe2O3, Cr2O3 and ZnO nanoparticles (NPs) stabilized with polyacrylic acid. The analytical performance of helium collision cell SP-ICP-MS was also assessed in detail. Although the sensitivity of the measurement for medium or low mass analytes decreased when the collision cell was used, the repeatability of the signal remained surprisingly good (3-6% RSD) even when NP signals were less than 50 counts and the acquisition time was kept as low as 100 s. In the helium mode, the size detection limit values were found to be 39 nm for Cr2O3, 15 nm for Fe2O3, 20 nm for ZnO and 35 nm for Ag NPs. These values are only 10-15% larger than comparable values found in no gas mode.

AB - In the present study, the applicability of single particle inductively coupled plasma mass spectroscopy (SP-ICP-MS) to the characterization of nano-dispersions is investigated in cases when the measurements are complicated by isobaric or polyatomic interferences. The specific classes of problems associated with spectral interferences in SP-ICP-MS measurements are described and the ways potentially applicable to the mitigation of these are discussed. Detailed experimental data are presented for the dispersions of Fe2O3, Cr2O3 and ZnO nanoparticles (NPs) stabilized with polyacrylic acid. The analytical performance of helium collision cell SP-ICP-MS was also assessed in detail. Although the sensitivity of the measurement for medium or low mass analytes decreased when the collision cell was used, the repeatability of the signal remained surprisingly good (3-6% RSD) even when NP signals were less than 50 counts and the acquisition time was kept as low as 100 s. In the helium mode, the size detection limit values were found to be 39 nm for Cr2O3, 15 nm for Fe2O3, 20 nm for ZnO and 35 nm for Ag NPs. These values are only 10-15% larger than comparable values found in no gas mode.

UR - http://www.scopus.com/inward/record.url?scp=84973601968&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84973601968&partnerID=8YFLogxK

U2 - 10.1039/c5ja00501a

DO - 10.1039/c5ja00501a

M3 - Article

AN - SCOPUS:84973601968

VL - 31

SP - 1112

EP - 1122

JO - Journal of Analytical Atomic Spectrometry

JF - Journal of Analytical Atomic Spectrometry

SN - 0267-9477

IS - 5

ER -